› 1sxz

X-ray diffraction
2.05Å resolution

Reduced bovine superoxide dismutase at pH 5.0 complexed with azide

Released:
DOI: 10.2210/pdb1sxz/pdb
PDB entry 1sxz coloured by chain, front view.
PDB entry 1sxz coloured by chain, side view.
PDB entry 1sxz coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystallographic determination of reduced bovine superoxide dismutase at pH 5.0 and of anion binding to its active site
Ferraroni M, Rypniewski WR, Bruni B, Orioli P, Mangani S
J. Biol. Inorg. Chem. 3 411-422 (1998)

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Cu-Zn] Chains: A, B
Molecule details ›
Chains: A, B
Length: 151 amino acids
Theoretical weight: 15.57 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00442 (Residues: 2-152; Coverage: 99%)
Gene name: SOD1
Sequence domains: Copper/zinc superoxide dismutase (SODC)
Structure domains: Superoxide dismutase, copper/zinc binding domain

Ligands and Environments

4 bound ligands:
Ligand CU 2 x CU
Ligand ZN 2 x ZN
Ligand CA 2 x CA
Ligand AZI 2 x AZI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2221
Unit cell:
a: 104.6Å b: 197.5Å c: 50.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.166 not available

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Citations

2 mentions without citation

Structural evidence for a copper-bound carbonate intermediate in the peroxidase and dismutase activities of superoxide dismutase.
Strange et al. (2012)
1 more