Structure analysis

NFKB P50 HOMODIMER BOUND TO DNA

X-ray diffraction
2.6Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule
1 distinct DNA molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 35700 Å2
Buried surface area: 7100 Å2
Dissociation area: 3,600 Å2
Dissociation energy (ΔGdiss): 28 kcal/mol
Dissociation entropy (TΔSdiss): 37 kcal/mol
Interface energy (ΔGint): -33 kcal/mol
Symmetry number: 2

Macromolecules

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Name: DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3')
Representative chains: D
Length: 19 nucleotides
Theoretical weight: 5.88 KDa

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