› 1suj

X-ray diffraction
2.38Å resolution

X-ray crystal structure of ambystoma tigrinum cone arrestin

Released:
DOI: 10.2210/pdb1suj/pdb
PDB entry 1suj coloured by chain, front view.
PDB entry 1suj coloured by chain, side view.
PDB entry 1suj coloured by chain, top view.
Source organism: Ambystoma tigrinum
Primary publication:
Crystal structure of cone arrestin at 2.3A: evolution of receptor specificity.
Sutton RB, Vishnivetskiy SA, Robert J, Hanson SM, Raman D, Knox BE, Kono M, Navarro J, Gurevich VV
J Mol Biol 354 1069-80 (2005)
PMID: 16289201

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192945 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arrestin-C Chain: A
Molecule details ›
Chain: A
Length: 392 amino acids
Theoretical weight: 43.96 KDa
Source organism: Ambystoma tigrinum
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9PTE7 (Residues: 1-392; Coverage: 100%)
Gene name: ARR2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P212121
Unit cell:
a: 70.762Å b: 75.049Å c: 79.059Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.246 0.297
Expression system: Escherichia coli BL21

Quick links

Citations

30 review citations

Regulation of receptor trafficking by GRKs and arrestins.
Moore et al. (2007)
29 more

6 mentions without citation

The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
Peterson et al. (2017)
5 more