Function and Biology

Cyrstal Structure of Cytochrome c Peroxidase Mutant: CcPK2M3

Source organism: Saccharomyces cerevisiae
Biochemical function: heme binding
Biological process: cellular response to oxidative stress
Cellular component: not assigned

EC 1.11.1.5: Cytochrome-c peroxidase

Reaction catalysed:
2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O
Systematic name:
Ferrocytochrome-c:hydrogen-peroxide oxidoreductase
Alternative Name(s):
  • Apocytochrome c peroxidase
  • Cytochrome c peroxidase
  • Cytochrome c-551 peroxidase
  • Cytochrome c-H(2)O oxidoreductase
  • Cytochrome peroxidase
  • Mesocytochrome c peroxidase azide
  • Mesocytochrome c peroxidase cyanate
  • Mesocytochrome c peroxidase cyanide

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00141
Domain description: Peroxidase
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
The deposited structure of PDB entry 1stq contains 1 copy of Pfam domain PF00141 (Peroxidase) in Cytochrome c peroxidase, mitochondrial. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002016
Domain description: Haem peroxidase
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
IPR002207
Domain description: Class I peroxidase
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
IPR019793
Domain description: Peroxidases heam-ligand binding site
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
IPR019794
Domain description: Peroxidase, active site
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
IPR044831
Domain description: Heme-binding peroxidase Ccp1-like
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
IPR010255
Domain description: Haem peroxidase superfamily
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial

Structure domains

CATH CATH domains
1.10.520.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Peroxidase; domain 1
Homology: Peroxidase; domain 1
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
The deposited structure of PDB entry 1stq contains 1 copy of CATH domain 1.10.520.10 (Peroxidase; domain 1) in Cytochrome c peroxidase, mitochondrial. Showing 1 copy in chain A.
1.10.420.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Peroxidase; domain 2
Homology: Peroxidase, domain 2
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
The deposited structure of PDB entry 1stq contains 1 copy of CATH domain 1.10.420.10 (Peroxidase; domain 2) in Cytochrome c peroxidase, mitochondrial. Showing 1 copy in chain A.
SCOP SCOP annotation
48114
Class: All alpha proteins
Fold: Heme-dependent peroxidases
Superfamily: Heme-dependent peroxidases
Occurring in:
  1. Cytochrome c peroxidase, mitochondrial
The deposited structure of PDB entry 1stq contains 1 copy of SCOP domain 48114 (CCP-like) in Cytochrome c peroxidase, mitochondrial. Showing 1 copy in chain A.