1ssc

X-ray diffraction
2Å resolution

THE 1.6 ANGSTROMS STRUCTURE OF A SEMISYNTHETIC RIBONUCLEASE CRYSTALLIZED FROM AQUEOUS ETHANOL. COMPARISON WITH CRYSTALS FROM SALT SOLUTIONS AND WITH RNASE A FROM AQUEOUS ALCOHOL SOLUTIONS

Released:

Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.38 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 27-138; Coverage: 90%)
Gene names: RNASE1, RNS1
Structure domains: Ribonuclease A-like domain
Ribonuclease pancreatic Chain: B
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.23 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 140-150; Coverage: 9%)
Gene names: RNASE1, RNS1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 30.36Å b: 38.34Å c: 53.55Å
α: 90° β: 106.35° γ: 90°
R-values:
R R work R free
0.166 not available not available
Expression system: Not provided