› 1sq1

X-ray diffraction
2.8Å resolution

Crystal Structure of the Chorismate Synthase from Campylobacter jejuni, Northeast Structural Genomics Target BR19

Released:
DOI: 10.2210/pdb1sq1/pdb
PDB entry 1sq1 coloured by chain, front view.
PDB entry 1sq1 coloured by chain, side view.
PDB entry 1sq1 coloured by chain, top view.
Source organism: Campylobacter jejuni
Entry authors: Forouhar F, Lee I, Vorobiev SM, Xiao R, Acton TB, Montelione GT, Tong L, Hunt JF, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reaction catalysed: 
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192914 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate synthase Chain: A
Molecule details ›
Chain: A
Length: 370 amino acids
Theoretical weight: 40.71 KDa
Source organism: Campylobacter jejuni
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9PM41 (Residues: 1-362; Coverage: 100%)
Gene names: Cj1634c, aroC
Sequence domains: Chorismate synthase
Structure domains: Chorismate synthase AroC

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: I4122
Unit cell:
a: 73.6Å b: 73.6Å c: 338.559Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.279
Expression system: Escherichia coli

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