Solution NMR

NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Polypyrimidine tract-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P26599 (Residues: 147-301; Coverage: 29%)
Gene names: PTB, PTBP1
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: Hybrid distance geometry/simulated annealing
Expression system: Escherichia coli