1sj2

X-ray diffraction
2.41Å resolution

Crystal structure of Mycobacterium tuberculosis catalase-peroxidase

Released:

Function and Biology Details

Reaction catalysed:
2 H(2)O(2) = O(2) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Catalase-peroxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 743 amino acids
Theoretical weight: 81.06 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIE5 (Residues: 2-740; Coverage: 100%)
Gene names: MTCY180.10, Rv1908c, katG
Sequence domains: Peroxidase
Structure domains:

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P42212
Unit cell:
a: 150.33Å b: 150.33Å c: 154.281Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.268
Expression system: Escherichia coli