1sfp › Citations

The crystal structures of two spermadhesins reveal the CUB domain fold.

Romero A, Romão MJ, Varela PF, Kölln I, Dias JM, Carvalho AL, Sanz L, Töpfer-Petersen E, Calvete JJ
Nat Struct Biol 4 783-8 (1997)
Cited: 90 times
EuropePMC logo PMID: 9334740

Abstract

Spermadhesins, 12,000-14,000 M(r) mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 A and 1.9 A resolution respectively.

Articles - 1sfp mentioned but not cited (8)

  1. Ab initio modeling of small proteins by iterative TASSER simulations. Wu S, Skolnick J, Zhang Y. BMC Biol 5 17 (2007)
  2. Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2. Feinberg H, Uitdehaag JC, Davies JM, Wallis R, Drickamer K, Weis WI. EMBO J. 22 2348-2359 (2003)
  3. Discordant and chameleon sequences: their distribution and implications for amyloidogenicity. Gendoo DM, Harrison PM. Protein Sci 20 567-579 (2011)
  4. Design of an optimal Chebyshev-expanded discrimination function for globular proteins. Fain B, Xia Y, Levitt M. Protein Sci 11 2010-2021 (2002)
  5. Multiple structure alignment and consensus identification for proteins. Ilinkin I, Ye J, Janardan R. BMC Bioinformatics 11 71 (2010)
  6. Calculating ensemble averaged descriptions of protein rigidity without sampling. González LC, Wang H, Livesay DR, Jacobs DJ. PLoS One 7 e29176 (2012)
  7. Identify High-Quality Protein Structural Models by Enhanced K-Means. Wu H, Li H, Jiang M, Chen C, Lv Q, Wu C. Biomed Res Int 2017 7294519 (2017)
  8. A Probabilistic Graphical Model for Ab Initio Folding. Zhao F, Peng J, Debartolo J, Freed KF, Sosnick TR, Xu J. Res Comput Mol Biol 5541 59-73 (2009)


Reviews citing this publication (20)

  1. Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion. Wassarman PM. Cell 96 175-183 (1999)
  2. Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family. Reigstad LJ, Varhaug JE, Lillehaug JR. FEBS J. 272 5723-5741 (2005)
  3. ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis. Jones GC, Riley GP. Arthritis Res. Ther. 7 160-169 (2005)
  4. Spermadhesins: a new protein family. Facts, hypotheses and perspectives. Töpfer-Petersen E, Romero A, Varela PF, Ekhlasi-Hundrieser M, Dostàlovà Z, Sanz L, Calvete JJ. Andrologia 30 217-224 (1998)
  5. Megalin- and cubilin-mediated endocytosis of protein-bound vitamins, lipids, and hormones in polarized epithelia. Moestrup SK, Verroust PJ. Annu. Rev. Nutr. 21 407-428 (2001)
  6. Salivary agglutinin/glycoprotein-340/DMBT1: a single molecule with variable composition and with different functions in infection, inflammation and cancer. Ligtenberg AJ, Veerman EC, Nieuw Amerongen AV, Mollenhauer J. Biol. Chem. 388 1275-1289 (2007)
  7. The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins. Birn H. Am. J. Physiol. Renal Physiol. 291 F22-36 (2006)
  8. Non-traditional roles of ubiquitin-proteasome system in fertilization and gametogenesis. Sakai N, Sawada MT, Sawada H. Int. J. Biochem. Cell Biol. 36 776-784 (2004)
  9. The role of the kidney in lipid metabolism. Moestrup SK, Nielsen LB. Curr. Opin. Lipidol. 16 301-306 (2005)
  10. Cubilin, a high-density lipoprotein receptor. Moestrup SK, Kozyraki R. Curr. Opin. Lipidol. 11 133-140 (2000)
  11. Structural biology of the C1 complex of complement unveils the mechanisms of its activation and proteolytic activity. Arlaud GJ, Gaboriaud C, Thielens NM, Budayova-Spano M, Rossi V, Fontecilla-Camps JC. Mol. Immunol. 39 383-394 (2002)
  12. Deleted in malignant brain tumors-1 protein (DMBT1): a pattern recognition receptor with multiple binding sites. Ligtenberg AJ, Karlsson NG, Veerman EC. Int J Mol Sci 11 5212-5233 (2010)
  13. Molecules on the sperm's route to fertilization. Töpfer-Petersen E. J. Exp. Zool. 285 259-266 (1999)
  14. The roles of cubilin and megalin, two multiligand receptors, in proximal tubule function: possible implication in the progression of renal disease. Verroust PJ, Kozyraki R. Curr. Opin. Nephrol. Hypertens. 10 33-38 (2001)
  15. Structure and properties of the Ca(2+)-binding CUB domain, a widespread ligand-recognition unit involved in major biological functions. Gaboriaud C, Gregory-Pauron L, Teillet F, Thielens NM, Bally I, Arlaud GJ. Biochem. J. 439 185-193 (2011)
  16. How calcium makes endocytic receptors attractive. Andersen CB, Moestrup SK. Trends Biochem. Sci. 39 82-90 (2014)
  17. Assembly of C1 and the MBL- and ficolin-MASP complexes: structural insights. Gaboriaud C, Teillet F, Gregory LA, Thielens NM, Arlaud GJ. Immunobiology 212 279-288 (2007)
  18. Cell surface changes in the egg at fertilization. Wessel GM, Wong JL. Mol. Reprod. Dev. 76 942-953 (2009)
  19. Sperm Functional Genome Associated With Bull Fertility. Özbek M, Hitit M, Kaya A, Jousan FD, Memili E. Front Vet Sci 8 610888 (2021)
  20. The biology of SCUBE. Lin YC, Sahoo BK, Gau SS, Yang RB. J Biomed Sci 30 33 (2023)

Articles citing this publication (62)

  1. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. Dev. Cell 5 45-57 (2003)
  2. Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1. Aminoff M, Carter JE, Chadwick RB, Johnson C, Gräsbeck R, Abdelaal MA, Broch H, Jenner LB, Verroust PJ, Moestrup SK, de la Chapelle A, Krahe R. Nat. Genet. 21 309-313 (1999)
  3. Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D. Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, Kliem A, Reid KB, Poustka A, Skjodt K. Proc. Natl. Acad. Sci. U.S.A. 96 10794-10799 (1999)
  4. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C. EMBO J. 26 4902-4912 (2007)
  5. Identity and transfer of male reproductive gland proteins of the dengue vector mosquito, Aedes aegypti: potential tools for control of female feeding and reproduction. Sirot LK, Poulson RL, McKenna MC, Girnary H, Wolfner MF, Harrington LC. Insect Biochem. Mol. Biol. 38 176-189 (2008)
  6. Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. Ng D, Pitcher GM, Szilard RK, Sertié A, Kanisek M, Clapcote SJ, Lipina T, Kalia LV, Joo D, McKerlie C, Cortez M, Roder JC, Salter MW, McInnes RR. PLoS Biol. 7 e41 (2009)
  7. Comparative structural modeling and inference of conserved protein classes in Drosophila seminal fluid. Mueller JL, Ripoll DR, Aquadro CF, Wolfner MF. Proc. Natl. Acad. Sci. U.S.A. 101 13542-13547 (2004)
  8. Fates and targets of male accessory gland proteins in mated female Drosophila melanogaster. Ravi Ram K, Ji S, Wolfner MF. Insect Biochem. Mol. Biol. 35 1059-1071 (2005)
  9. The species-specific egg receptor for sea urchin sperm adhesion is EBR1,a novel ADAMTS protein. Kamei N, Glabe CG. Genes Dev. 17 2502-2507 (2003)
  10. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Scherl-Mostageer M, Sommergruber W, Abseher R, Hauptmann R, Ambros P, Schweifer N. Oncogene 20 4402-4408 (2001)
  11. Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions. Tao Z, Peng Y, Nolasco L, Cal S, Lopez-Otin C, Li R, Moake JL, López JA, Dong JF. Blood 106 4139-4145 (2005)
  12. CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Uekita T, Tanaka M, Takigahira M, Miyazawa Y, Nakanishi Y, Kanai Y, Yanagihara K, Sakai R. Am. J. Pathol. 172 1729-1739 (2008)
  13. Spermadhesin AQN1 is a candidate receptor molecule involved in the formation of the oviductal sperm reservoir in the pig. Ekhlasi-Hundrieser M, Gohr K, Wagner A, Tsolova M, Petrunkina A, Töpfer-Petersen E. Biol. Reprod. 73 536-545 (2005)
  14. Adhesion or plasmin regulates tyrosine phosphorylation of a novel membrane glycoprotein p80/gp140/CUB domain-containing protein 1 in epithelia. Brown TA, Yang TM, Zaitsevskaia T, Xia Y, Dunn CA, Sigle RO, Knudsen B, Carter WG. J. Biol. Chem. 279 14772-14783 (2004)
  15. Influence of porcine spermadhesins on the susceptibility of boar spermatozoa to high dilution. Centurion F, Vazquez JM, Calvete JJ, Roca J, Sanz L, Parrilla I, Garcia EM, Martinez EA. Biol. Reprod. 69 640-646 (2003)
  16. Identification of the C1q-binding Sites of Human C1r and C1s: a refined three-dimensional model of the C1 complex of complement. Bally I, Rossi V, Lunardi T, Thielens NM, Gaboriaud C, Arlaud GJ. J. Biol. Chem. 284 19340-19348 (2009)
  17. The role of stallion seminal proteins in fertilisation. Töpfer-Petersen E, Ekhlasi-Hundrieser M, Kirchhoff C, Leeb T, Sieme H. Anim. Reprod. Sci. 89 159-170 (2005)
  18. Insights into how CUB domains can exert specific functions while sharing a common fold: conserved and specific features of the CUB1 domain contribute to the molecular basis of procollagen C-proteinase enhancer-1 activity. Blanc G, Font B, Eichenberger D, Moreau C, Ricard-Blum S, Hulmes DJ, Moali C. J Biol Chem 282 16924-16933 (2007)
  19. Structural similarity and functional diversity in proteins containing the legume lectin fold. Chandra NR, Prabu MM, Suguna K, Vijayan M. Protein Eng. 14 857-866 (2001)
  20. Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution. Mathews FS, Gordon MM, Chen Z, Rajashankar KR, Ealick SE, Alpers DH, Sukumar N. Proc. Natl. Acad. Sci. U.S.A. 104 17311-17316 (2007)
  21. Immunohistochemical detection of salivary agglutinin/gp-340 in human parotid, submandibular, and labial salivary glands. Bikker FJ, Ligtenberg AJ, van der Wal JE, van den Keijbus PA, Holmskov U, Veerman EC, Nieuw Amerongen AV. J. Dent. Res. 81 134-139 (2002)
  22. Spermadhesin PSP-I/PSP-II heterodimer and its isolated subunits induced neutrophil migration into the peritoneal cavity of rats. Assreuy AM, Calvete JJ, Alencar NM, Cavada BS, Rocha-Filho DR, Melo SC, Cunha FQ, Ribeiro RA. Biol. Reprod. 67 1796-1803 (2002)
  23. Expression of spermadhesin genes in porcine male and female reproductive tracts. Ekhlasi-Hundrieser M, Sinowatz F, Greiser De Wilke I, Waberski D, Töpfer-Petersen E. Mol. Reprod. Dev. 61 32-41 (2002)
  24. Major proteins of boar seminal plasma as a tool for biotechnological preservation of spermatozoa. Caballero I, Vazquez JM, García EM, Parrilla I, Roca J, Calvete JJ, Sanz L, Martínez EA. Theriogenology 70 1352-1355 (2008)
  25. Structural characterization of the oligosaccharide chains of native and crystallized boar seminal plasma spermadhesin PSP-I and PSP-II glycoforms. Nimtz M, Grabenhorst E, Conradt HS, Sanz L, Calvete JJ. Eur. J. Biochem. 265 703-718 (1999)
  26. Folding and activity of recombinant human procollagen C-proteinase enhancer. Moschcovich L, Bernocco S, Font B, Rivkin H, Eichenberger D, Chejanovsky N, Hulmes DJ, Kessler E. Eur. J. Biochem. 268 2991-2996 (2001)
  27. Does seminal plasma PSP-I/PSP-II spermadhesin modulate the ability of boar spermatozoa to penetrate homologous oocytes in vitro? Caballero I, Vazquez JM, Gil MA, Calvete JJ, Roca J, Sanz L, Parrilla I, Garcia EM, Rodriguez-Martinez H, Martinez EA. J. Androl. 25 1004-1012 (2004)
  28. Identification and expression of a novel type I procollagen C-proteinase enhancer protein gene from the glaucoma candidate region on 3q21-q24. Xu H, Acott TS, Wirtz MK. Genomics 66 264-273 (2000)
  29. Isolated ZP-N domains constitute the N-terminal extensions of Zona Pellucida proteins. Callebaut I, Mornon JP, Monget P. Bioinformatics 23 1871-1874 (2007)
  30. Oogenesis: single cell development and differentiation. Song JL, Wong JL, Wessel GM. Dev. Biol. 300 385-405 (2006)
  31. The first crystal structure of a Mimosoideae lectin reveals a novel quaternary arrangement of a widespread domain. Gallego del Sol F, Nagano C, Cavada BS, Calvete JJ. J. Mol. Biol. 353 574-583 (2005)
  32. Binding of mannose-6-phosphate and heparin by boar seminal plasma PSP-II, a member of the spermadhesin protein family. Solís D, Romero A, Jiménez M, Díaz-Mauriño T, Calvete JJ. FEBS Lett. 431 273-278 (1998)
  33. Evolution of the spermadhesin gene family. Haase B, Schlötterer C, Hundrieser ME, Kuiper H, Distl O, Töpfer-Petersen E, Leeb T. Gene 352 20-29 (2005)
  34. Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney. Christensen EI, Raciti D, Reggiani L, Verroust PJ, Brändli AW. Pflugers Arch. 456 1163-1176 (2008)
  35. Seminal plasma proteins inhibit in vitro- and cooling-induced capacitation in boar spermatozoa. Vadnais ML, Roberts KP. Reprod. Fertil. Dev. 22 893-900 (2010)
  36. Rendezvin: An essential gene encoding independent, differentially secreted egg proteins that organize the fertilization envelope proteome after self-association. Wong JL, Wessel GM. Mol. Biol. Cell 17 5241-5252 (2006)
  37. Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Gonçalves CM, Castro MA, Henriques T, Oliveira MI, Pinheiro HC, Oliveira C, Sreenu VB, Evans EJ, Davis SJ, Moreira A, Carmo AM. Mol. Immunol. 46 2585-2596 (2009)
  38. Buck (Capra hircus) genes encode new members of the spermadhesin family. Melo LM, Teixeira DI, Havt A, da Cunha RM, Martins DB, Castelletti CH, de Souza PR, Filho JL, Freitas VJ, Cavada BS, Rádis-Baptista G. Mol. Reprod. Dev. 75 8-16 (2008)
  39. Identification of novel isoforms of vitellogenin expressed in ascidian eggs. Akasaka M, Kato KH, Kitajima K, Sawada H. J. Exp. Zool. B Mol. Dev. Evol. 320 118-128 (2013)
  40. Ovochymase in amphioxus Branchiostoma belcheri is an ovary-specific trypsin-like serine protease with an antibacterial activity. Gao K, Zhang S. Dev. Comp. Immunol. 33 1219-1228 (2009)
  41. Research Support, Non-U.S. Gov't Structure and function of secretory proteins of the male genital tract. Töpfer-Petersen E, Ekhlasi-Hundrieser M, Tsolova M, Leeb T, Kirchhoff C, Müller P. Andrologia 37 202-204 (2005)
  42. Three-dimensional model of the honeybee venom allergen Api m 7: structural and functional insights. Georgieva D, Greunke K, Betzel C. Mol Biosyst 6 1056-1060 (2010)
  43. Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability. Zhou Z, Yeh HC, Jing H, Wang C, Tao Z, Choi H, Aboulfatova K, Li R, Dong JF. Thromb. Haemost. 105 21-30 (2011)
  44. Localization of porcine seminal plasma (PSP) proteins in the boar reproductive tract and spermatozoa. Manásková P, Jonáková V. J. Reprod. Immunol. 78 40-48 (2008)
  45. Structural Implications for the Formation and Function of the Complement Effector Protein iC3b. Papanastasiou M, Koutsogiannaki S, Sarigiannis Y, Geisbrecht BV, Ricklin D, Lambris JD. J. Immunol. 198 3326-3335 (2017)
  46. Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight into Ternary Complex Formation with LRP6 and Dickkopf. Zebisch M, Jackson VA, Zhao Y, Jones EY. Structure 24 1599-1605 (2016)
  47. Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13. Zhou Z, Jing H, Tao Z, Choi H, Aboulfatova K, Moake J, Li R, Dong JF. Thromb. Res. 124 323-327 (2009)
  48. Localization and expression of spermadhesin PSP-I/PSP-II subunits in the reproductive organs of the boar. García EM, Vázquez JM, Parrilla I, Ortega MD, Calvete JJ, Sanz L, Martínez EA, Roca J, Rodríguez-Martínez H. Int. J. Androl. 31 408-417 (2008)
  49. A novel human dendritic cell-derived C1r-like serine protease analog inhibits complement-mediated cytotoxicity. Lin N, Liu S, Li N, Wu P, An H, Yu Y, Wan T, Cao X. Biochem. Biophys. Res. Commun. 321 329-336 (2004)
  50. Seminal plasma proteins and their relationship with sperm motility and morphology in boars. De Lazari FL, Sontag ER, Schneider A, Moura AAA, Vasconcelos FR, Nagano CS, Mattos RC, Jobim MIM, Bustamante-Filho IC. Andrologia 51 e13222 (2019)
  51. The structure and function of thioester-containing proteins in arthropods. Williams M, Baxter R. Biophys Rev 6 261-272 (2014)
  52. Analysis of the stability of the spermadhesin PSP-I/PSP-II heterodimer. Effects of Zn2+ and acidic pH. Campanero-Rhodes MA, Menéndez M, Sáiz JL, Sanz L, Calvete JJ, Solís D. FEBS J. 272 5663-5670 (2005)
  53. Characterization of a cDNA encoding RP43, a CUB-domain-containing protein from the tube of Riftia pachyptila (Vestimentifera), and distribution of its transcript. Chamoy L, Nicolaï M, Quennedey B, Gaill F, Delachambre J. Biochem. J. 350 Pt 2 421-427 (2000)
  54. Positive selection and comparative molecular evolution of reproductive proteins from New Zealand tree weta (Orthoptera, Hemideina). Twort VG, Dennis AB, Park D, Lomas KF, Newcomb RD, Buckley TR. PLoS ONE 12 e0188147 (2017)
  55. Sperm Lysozyme-Like Protein 1 (SLLP1), an intra-acrosomal oolemmal-binding sperm protein, reveals filamentous organization in protein crystal form. Zheng H, Mandal A, Shumilin IA, Chordia MD, Panneerdoss S, Herr JC, Minor W. Andrology 3 756-771 (2015)
  56. Letter A bug in CUB's clothing: similarity between clostridial CBMs and complement CUBs. Briggs DC, Day AJ. Trends Microbiol. 16 407-408 (2008)
  57. An avidin-like domain that does not bind biotin is adopted for oligomerization by the extracellular mosaic protein fibropellin. Yanai I, Yu Y, Zhu X, Cantor CR, Weng Z. Protein Sci. 14 417-423 (2005)
  58. Novel mutations in ADAMTS13 CUB domains cause abnormal pre-mRNA splicing and defective secretion of ADAMTS13. Jiang Y, Huang D, Kondo Y, Jiang M, Ma Z, Zhou L, Su J, Bai X, Ruan C, Wang Z, Xia L. J Cell Mol Med 24 4356-4361 (2020)
  59. Characterization of a novel thermostable phospholipase C from T. kodakarensis suitable for oil degumming. Marchisio F, Di Nardo L, Val DS, Cerminati S, Espariz M, Rasia RM, Menzella HG, Castelli ME. Appl Microbiol Biotechnol 106 5081-5091 (2022)
  60. Evolutionary and structural analyses of heterodimeric proteins composed of subunits with same fold. Sudha G, Naveenkumar N, Srinivasan N. Proteins 83 1766-1786 (2015)
  61. Supplementation of Schisandrin B in Semen Extender Improves Quality and Oxidation Resistance of Boar Spermatozoa Stored at 4 °C. Xie Y, Chen Z, Wang Y, Peng X, Feng N, Wang X, Tang Y, Li X, Xu C, Hu C. Animals (Basel) 13 848 (2023)
  62. The scavenging capacity of DMBT1 is impaired by germline deletions. Bikker FJ, End C, Ligtenberg AJM, Blaich S, Lyer S, Renner M, Wittig R, Nazmi K, van Nieuw Amerongen A, Poustka A, Veerman ECI, Mollenhauer J. Immunogenetics 69 401-407 (2017)


Quick links