1rzi

X-ray diffraction
2.9Å resolution

Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab 47e light chain Chains: A, C, E, G, I, K, M, O
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 212 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Human gammaherpesvirus 4
Structure domains: Immunoglobulins
Fab 47e heavy chain Chains: B, D, F, H, J, L, N, P
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 230 amino acids
Theoretical weight: 24.16 KDa
Source organism: Homo sapiens
Expression system: Human gammaherpesvirus 4
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P1
Unit cell:
a: 73.43Å b: 111.645Å c: 133.309Å
α: 85.48° β: 90° γ: 89.71°
R-values:
R R work R free
0.233 0.233 0.321
Expression system: Human gammaherpesvirus 4