1rv4

X-ray diffraction
2.95Å resolution

E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine hydroxymethyltransferase, cytosolic Chains: A, B
Molecule details ›
Chains: A, B
Length: 483 amino acids
Theoretical weight: 52.9 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P07511 (Residues: 2-484; Coverage: 100%)
Gene name: SHMT1
Sequence domains: Serine hydroxymethyltransferase
Structure domains:

Ligands and Environments


Cofactor: Ligand PLP 2 x PLP
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P41212
Unit cell:
a: 115.04Å b: 115.04Å c: 158.39Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 0.241
Expression system: Escherichia coli