X-ray diffraction
1.4Å resolution

Crystal structure (G) of native cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at APS beamline 19-ID

Source organism: Mus musculus
Primary publication:
Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.
Proc. Natl. Acad. Sci. U.S.A. 101 2247-52 (2004)
PMID: 14982995

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
immunoglobulin igg2a, heavy chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.22 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig gamma-2A chain C region, membrane-bound form Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.82 KDa
Source organism: Mus musculus
  • Canonical: P01865 (Residues: 1-102; Coverage: 26%)
Gene name: Igh-1a
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 64.197Å b: 64.197Å c: 266.475Å
α: 90° β: 90° γ: 90°
R R work R free
0.161 0.161 0.212