X-ray diffraction
2.5Å resolution

RmlC (dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase) crystal structure from Pseudomonas aeruginosa, apo structure

Source organism: Pseudomonas aeruginosa
Entry authors: Dong CJ, Naismith JH

Function and Biology Details

Reaction catalysed:
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
dTDP-4-dehydrorhamnose 3,5-epimerase Chain: A
Molecule details ›
Chain: A
Length: 184 amino acids
Theoretical weight: 21.08 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9HU21 (Residues: 1-181; Coverage: 100%)
Gene names: PA5164, rmlC
Sequence domains: dTDP-4-dehydrorhamnose 3,5-epimerase
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS
Spacegroup: P41212
Unit cell:
a: 57.833Å b: 57.833Å c: 161.62Å
α: 90° β: 90° γ: 90°
R R work R free
0.25 0.23 0.29
Expression system: Escherichia coli BL21(DE3)