1rl4

X-ray diffraction
2.18Å resolution

Plasmodium falciparum peptide deformylase complex with inhibitor

Released:

Function and Biology Details

Reaction catalysed:
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide deformylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 188 amino acids
Theoretical weight: 22.27 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8I372 (Residues: 59-236; Coverage: 74%)
Gene name: PF3D7_0907900
Structure domains: Peptide deformylase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P65
Unit cell:
a: 102.317Å b: 102.317Å c: 118.339Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.197 0.212
Expression system: Escherichia coli BL21(DE3)