X-ray diffraction
2.1Å resolution

Crystal Structure of FLT3


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Receptor-type tyrosine-protein kinase FLT3 Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 39.8 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
  • Canonical: P36888 (Residues: 564-958; Coverage: 36%)
Gene names: CD135, FLK2, FLT3, STK1
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P43212
Unit cell:
a: 80.651Å b: 80.651Å c: 150.12Å
α: 90° β: 90° γ: 90°
R R work R free
0.23 0.21 0.248
Expression system: Trichoplusia ni