1rj7

X-ray diffraction
2.3Å resolution

Crystal structure of EDA-A1

Released:

Function and Biology Details

Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-187776 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ectodysplasin-A, secreted form Chains: A, B, D, E, F, G, H, I, J, K, L, M
Molecule details ›
Chains: A, B, D, E, F, G, H, I, J, K, L, M
Length: 163 amino acids
Theoretical weight: 17.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92838 (Residues: 233-391; Coverage: 41%)
Gene names: ED1, EDA, EDA2
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 53.657Å b: 279.687Å c: 54.175Å
α: 90° β: 91.36° γ: 90°
R-values:
R R work R free
0.201 0.194 0.26
Expression system: Escherichia coli BL21(DE3)