› 1rgx

X-ray diffraction
1.79Å resolution

Crystal Structure of resisitin

Released:
DOI: 10.2210/pdb1rgx/pdb
PDB entry 1rgx coloured by chain, front view.
PDB entry 1rgx coloured by chain, side view.
PDB entry 1rgx coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Disulfide-dependent multimeric assembly of resistin family hormones.
Patel SD, Rajala MW, Rossetti L, Scherer PE, Shapiro L
Science 304 1154-8 (2004)
PMID: 15155948

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-189372 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Resistin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 114 amino acids
Theoretical weight: 12.5 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99P87 (Residues: 1-114; Coverage: 100%)
Gene names: Fizz3, Retn
Sequence domains: Resistin
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2
Unit cell:
a: 49.021Å b: 52.475Å c: 96.609Å
α: 90° β: 96.53° γ: 90°
R-values:
R R work R free
0.206 0.204 0.245
Expression system: Homo sapiens

Quick links

Citations

70 review citations

Adipokines in inflammation and metabolic disease.
Ouchi et al. (2011)
69 more

2 mentions without citation

In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure.
Elkhattabi et al. (2019)
1 more