1r9c

X-ray diffraction
1.83Å resolution

Crystal Structure of Fosfomycin Resistance Protein FosX from Mesorhizobium Loti

Released:
Source organism: Mesorhizobium loti

Function and Biology Details

Reaction catalysed:
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fosfomycin resistance protein FosX Chains: A, B
Molecule details ›
Chains: A, B
Length: 139 amino acids
Theoretical weight: 16.21 KDa
Source organism: Mesorhizobium loti
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q98GG1 (Residues: 1-139; Coverage: 100%)
Gene names: fosX, mlr3345
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 45.034Å b: 84.024Å c: 66.861Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.202 0.243
Expression system: Escherichia coli BL21(DE3)