1r52

X-ray diffraction
2.89Å resolution

Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae

Released:

Function and Biology Details

Reaction catalysed:
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 382 amino acids
Theoretical weight: 41.72 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P28777 (Residues: 1-376; Coverage: 100%)
Gene names: ARO2, YGL148W
Sequence domains: Chorismate synthase
Structure domains: Chorismate synthase AroC

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P1
Unit cell:
a: 57.816Å b: 75.599Å c: 91.327Å
α: 114.44° β: 108.43° γ: 89.98°
R-values:
R R work R free
0.19 0.188 0.224
Expression system: Escherichia coli