› 1qyy

X-ray diffraction
2.8Å resolution

Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution

Released:
DOI: 10.2210/pdb1qyy/pdb
PDB entry 1qyy coloured by chain, front view.
PDB entry 1qyy coloured by chain, side view.
PDB entry 1qyy coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Varughese KI, Ruggeri ZM, Celikel R
Acta Crystallogr D Biol Crystallogr 60 405-11 (2004)
PMID: 14993663

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139560 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Glycocalicin Chains: A, G
Molecule details ›
Chains: A, G
Length: 290 amino acids
Theoretical weight: 32.31 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P07359 (Residues: 17-306; Coverage: 46%)
Gene name: GP1BA
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
2 bound ligands:
Ligand PT 3 x PT
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: P21
Unit cell:
a: 51.61Å b: 113.82Å c: 56.21Å
α: 90° β: 95.21° γ: 90°
R-values:
R R work R free
0.223 0.219 0.282
Expression system: Drosophila melanogaster

Quick links

Citations

3 review citations

Rolling cell adhesion.
McEver et al. (2010)
2 more

6 mentions without citation

Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib.
Blenner et al. (2014)
5 more