X-ray diffraction
1.8Å resolution

Crystal structure of native phosphoglucose isomerase from Pyrococcus furiosus


Function and Biology Details

Reaction catalysed:
D-glucose 6-phosphate = D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glucose-6-phosphate isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.51 KDa
Source organism: Pyrococcus furiosus
Expression system: Escherichia coli BL21
  • Canonical: P83194 (Residues: 1-189; Coverage: 100%)
Gene names: PF0196, pgiA
Sequence domains: Glucose-6-phosphate isomerase (GPI)
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P1
Unit cell:
a: 36Å b: 39.7Å c: 74.7Å
α: 73.7° β: 78.5° γ: 72.6°
R R work R free
0.197 0.194 0.249
Expression system: Escherichia coli BL21