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CRYSTAL STRUCTURE OF EHA2 (23-185)

X-ray diffraction
1.9Å resolution
PDB entry 1qu1 coloured by chain, front view.
PDB entry 1qu1 coloured by chain, side view.
PDB entry 1qu1 coloured by chain, top view.
Source organism: Influenza A virus
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hemagglutinin HA1 chain
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Multimeric state: homo trimer
Accessible surface area: 21765.23 Å2
Buried surface area: 12619.31 Å2
Dissociation area: 6,309.65 Å2
Dissociation energy (ΔGdiss): 91.17 kcal/mol
Dissociation entropy (TΔSdiss): 27.53 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-137029
Assembly 2
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Assembly Name: Hemagglutinin HA1 chain
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Multimeric state: homo trimer
Accessible surface area: 22684.53 Å2
Buried surface area: 13178.21 Å2
Dissociation area: 6,589.11 Å2
Dissociation energy (ΔGdiss): 94.86 kcal/mol
Dissociation entropy (TΔSdiss): 27.78 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-137029

Macromolecules

Hemagglutinin HA2 chain
Chains: A, B, C, D, E, F
Length: 155 amino acids
Theoretical weight: 18.06 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03437 (Residues: 376-530; Coverage: 28%)
Gene name: HA
InterPro:
CATH: Hemagglutinin Ectodomain; Chain B
SCOP: Influenza hemagglutinin (stalk)
Hemagglutinin HA2 chain in PDB entry 1qu1, assembly 1, front view.
Hemagglutinin HA2 chain in PDB entry 1qu1, assembly 1, side view.
Hemagglutinin HA2 chain in PDB entry 1qu1, assembly 1, top view.
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