1qsz

Solution NMR

THE VEGF-BINDING DOMAIN OF FLT-1 (MINIMIZED MEAN)

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vascular endothelial growth factor receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P17948 (Residues: 129-229; Coverage: 8%)
Gene names: FLT, FLT1, FRT, VEGFR1
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY/SIMULATED ANNEALING; MOLECULAR DYNAMICS
Expression system: Escherichia coli