1qlz

Solution NMR

Human prion protein

Released:
Source organism: Homo sapiens
Primary publication:
NMR solution structure of the human prion protein.
Proc. Natl. Acad. Sci. U.S.A. 97 145-50 (2000)
PMID: 10618385

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 22.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04156 (Residues: 23-230; Coverage: 90%)
Gene names: ALTPRP, PRIP, PRNP, PRP
Structure domains: Prion/Doppel protein, beta-ribbon domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)