› 1qhk

Solution NMR

N-TERMINAL DOMAIN OF SACCHAROMYCES CEREVISIAE RNASE HI REVEALS A FOLD WITH A RESEMBLANCE TO THE N-TERMINAL DOMAIN OF RIBOSOMAL PROTEIN L9

Released:
DOI: 10.2210/pdb1qhk/pdb
PDB entry 1qhk coloured by chain, ensemble of 20 models, front view.
PDB entry 1qhk coloured by chain, ensemble of 20 models, side view.
PDB entry 1qhk coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
NMR structure of the N-terminal domain of Saccharomyces cerevisiae RNase HI reveals a fold with a strong resemblance to the N-terminal domain of ribosomal protein L9.
Evans SP, Bycroft M
J Mol Biol 291 661-9 (1999)
PMID: 10448044

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease H Chain: A
Molecule details ›
Chain: A
Length: 47 amino acids
Theoretical weight: 5.38 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04740 (Residues: 5-51; Coverage: 14%)
Gene names: RNH1, YM9959.16, YMR234W
Sequence domains: Caulimovirus viroplasmin
Structure domains: Ribonuclease H1, N-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Ribonuclease H: the enzymes in eukaryotes.
Cerritelli et al. (2009)
15 other articles

4 mentions without citation

Phylogenomic analysis of the GIY-YIG nuclease superfamily.
Dunin-Horkawicz et al. (2006)
3 more