› 1qfd

Solution NMR

NMR SOLUTION STRUCTURE OF ALPHA-AMYLASE INHIBITOR (AAI)

Released:
DOI: 10.2210/pdb1qfd/pdb
PDB entry 1qfd coloured by chain, ensemble of 10 models, front view.
PDB entry 1qfd coloured by chain, ensemble of 10 models, side view.
PDB entry 1qfd coloured by chain, ensemble of 10 models, top view.
Source organism: Amaranthus hypochondriacus
Primary publication:
Solution structure of the major alpha-amylase inhibitor of the crop plant amaranth.
Lu S, Deng P, Liu X, Luo J, Han R, Gu X, Liang S, Wang X, Li F, Lozanov V, Patthy A, Pongor S
J Biol Chem 274 20473-8 (1999)
PMID: 10400675

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160408 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-amylase inhibitor AAI Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.6 KDa
Source organism: Amaranthus hypochondriacus
UniProt:
  • Canonical: P80403 (Residues: 1-32; Coverage: 100%)
Gene name: AAI

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

6 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
5 more

8 mentions without citation

Peptide-based protease inhibitors from plants.
Hellinger et al. (2019)
7 more