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Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.

Xia D, Yu CA, Kim H, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofer J
Science 277 60-6 (1997)
Cited: 477 times
EuropePMC logo PMID: 9204897

Abstract

On the basis of x-ray diffraction data to a resolution of 2.9 angstroms, atomic models of most protein components of the bovine cytochrome bc1 complex were built, including core 1, core 2, cytochrome b, subunit 6, subunit 7, a carboxyl-terminal fragment of cytochrome c1, and an amino-terminal fragment of the iron-sulfur protein. The positions of the four iron centers within the bc1 complex and the binding sites of the two specific respiratory inhibitors antimycin A and myxothiazol were identified. The membrane-spanning region of each bc1 complex monomer consists of 13 transmembrane helices, eight of which belong to cytochrome b. Closely interacting monomers are arranged as symmetric dimers and form cavities through which the inhibitor binding pockets can be accessed. The proteins core 1 and core 2 are structurally similar to each other and consist of two domains of roughly equal size and identical folding topology.

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  1. Bis-histidine-coordinated hemes in four-helix bundles: how the geometry of the bundle controls the axial imidazole plane orientations in transmembrane cytochromes of mitochondrial complexes II and III and related proteins. Berry EA, Walker FA. J Biol Inorg Chem 13 481-498 (2008)
  2. Structural basis of resistance to anti-cytochrome bc₁ complex inhibitors: implication for drug improvement. Esser L, Yu CA, Xia D. Curr Pharm Des 20 704-724 (2014)
  3. The road to the structure of the mitochondrial respiratory chain supercomplex. Caruana NJ, Stroud DA. Biochem Soc Trans 48 621-629 (2020)
  4. Overview of protein structural and functional folds. Sun PD, Foster CE, Boyington JC. Curr Protoc Protein Sci Chapter 17 Unit 17.1 (2004)

Articles - 1qcr mentioned but not cited (8)

  1. Mitochondrial translation requires folate-dependent tRNA methylation. Morscher RJ, Ducker GS, Li SH, Mayer JA, Gitai Z, Sperl W, Rabinowitz JD. Nature 554 128-132 (2018)
  2. MM-align: a quick algorithm for aligning multiple-chain protein complex structures using iterative dynamic programming. Mukherjee S, Zhang Y. Nucleic Acids Res 37 e83 (2009)
  3. Female and male gamete mitochondria are distinct and complementary in transcription, structure, and genome function. de Paula WB, Agip AN, Missirlis F, Ashworth R, Vizcay-Barrena G, Lucas CH, Allen JF. Genome Biol Evol 5 1969-1977 (2013)
  4. Mitochondrial complex III Rieske Fe-S protein processing and assembly. Fernandez-Vizarra E, Zeviani M. Cell Cycle 17 681-687 (2018)
  5. Adaptive threonine increase in transmembrane regions of mitochondrial proteins in higher primates. Kitazoe Y, Kishino H, Hasegawa M, Nakajima N, Thorne JL, Tanaka M. PLoS One 3 e3343 (2008)
  6. MitImpact 3: modeling the residue interaction network of the Respiratory Chain subunits. Castellana S, Biagini T, Petrizzelli F, Parca L, Panzironi N, Caputo V, Vescovi AL, Carella M, Mazza T. Nucleic Acids Res 49 D1282-D1288 (2021)
  7. The genome of the Antarctic-endemic copepod, Tigriopus kingsejongensis. Kang S, Ahn DH, Lee JH, Lee SG, Shin SC, Lee J, Min GS, Lee H, Kim HW, Kim S, Park H. Gigascience 6 1-9 (2017)
  8. Letter UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer. Zong S, Gu J, Liu T, Guo R, Wu M, Yang M. Protein Cell 9 586-591 (2018)


Reviews citing this publication (125)

  1. Membrane protein folding and stability: physical principles. White SH, Wimley WC. Annu Rev Biophys Biomol Struct 28 319-365 (1999)
  2. Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failure. Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL. J Mol Cell Cardiol 33 1065-1089 (2001)
  3. Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Brand MD. Exp Gerontol 35 811-820 (2000)
  4. Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. Sumimoto H. FEBS J 275 3249-3277 (2008)
  5. Helical membrane protein folding, stability, and evolution. Popot JL, Engelman DM. Annu Rev Biochem 69 881-922 (2000)
  6. The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems. Cross AR, Segal AW. Biochim Biophys Acta 1657 1-22 (2004)
  7. Metalloproteins containing cytochrome, iron-sulfur, or copper redox centers. Liu J, Chakraborty S, Hosseinzadeh P, Yu Y, Tian S, Petrik I, Bhagi A, Lu Y. Chem Rev 114 4366-4469 (2014)
  8. The cytochrome bc1 complex: function in the context of structure. Crofts AR. Annu Rev Physiol 66 689-733 (2004)
  9. Structure and function of cytochrome bc complexes. Berry EA, Guergova-Kuras M, Huang LS, Crofts AR. Annu Rev Biochem 69 1005-1075 (2000)
  10. Molecular recognition in thylakoid structure and function. Allen JF, Forsberg J. Trends Plant Sci 6 317-326 (2001)
  11. Physiological Functions of Cyclic Electron Transport Around Photosystem I in Sustaining Photosynthesis and Plant Growth. Yamori W, Shikanai T. Annu Rev Plant Biol 67 81-106 (2016)
  12. Heme on innate immunity and inflammation. Dutra FF, Bozza MT. Front Pharmacol 5 115 (2014)
  13. Superoxide generation by complex III: from mechanistic rationales to functional consequences. Bleier L, Dröse S. Biochim Biophys Acta 1827 1320-1331 (2013)
  14. Molecular mechanisms of cytochrome c biogenesis: three distinct systems. Kranz R, Lill R, Goldman B, Bonnard G, Merchant S. Mol Microbiol 29 383-396 (1998)
  15. Energy transduction: proton transfer through the respiratory complexes. Hosler JP, Ferguson-Miller S, Mills DA. Annu Rev Biochem 75 165-187 (2006)
  16. Mitochondrial Metabolism in Aging Heart. Lesnefsky EJ, Chen Q, Hoppel CL. Circ Res 118 1593-1611 (2016)
  17. Mitochondria: a hub of redox activities and cellular distress control. Kakkar P, Singh BK. Mol Cell Biochem 305 235-253 (2007)
  18. Bioenergetics of the Archaea. Schäfer G, Engelhard M, Müller V. Microbiol Mol Biol Rev 63 570-620 (1999)
  19. Structures and proton-pumping strategies of mitochondrial respiratory enzymes. Schultz BE, Chan SI. Annu Rev Biophys Biomol Struct 30 23-65 (2001)
  20. The assembly, regulation and function of the mitochondrial respiratory chain. Vercellino I, Sazanov LA. Nat Rev Mol Cell Biol 23 141-161 (2022)
  21. Protonmotive pathways and mechanisms in the cytochrome bc1 complex. Hunte C, Palsdottir H, Trumpower BL. FEBS Lett 545 39-46 (2003)
  22. Proton-coupled electron flow in protein redox machines. Dempsey JL, Winkler JR, Gray HB. Chem Rev 110 7024-7039 (2010)
  23. Structure, function, and assembly of heme centers in mitochondrial respiratory complexes. Kim HJ, Khalimonchuk O, Smith PM, Winge DR. Biochim Biophys Acta 1823 1604-1616 (2012)
  24. Crystallization of membrane proteins. Ostermeier C, Michel H. Curr Opin Struct Biol 7 697-701 (1997)
  25. Supramolecular Organization of Respiratory Complexes. Enríquez JA. Annu Rev Physiol 78 533-561 (2016)
  26. Fixing the Q cycle. Osyczka A, Moser CC, Dutton PL. Trends Biochem Sci 30 176-182 (2005)
  27. Mitochondrial protein import in plants. Signals, sorting, targeting, processing and regulation. Glaser E, Sjöling S, Tanudji M, Whelan J. Plant Mol Biol 38 311-338 (1998)
  28. pH-dependent regulation of electron transport and ATP synthesis in chloroplasts. Tikhonov AN. Photosynth Res 116 511-534 (2013)
  29. Transmembrane traffic in the cytochrome b6f complex. Cramer WA, Zhang H, Yan J, Kurisu G, Smith JL. Annu Rev Biochem 75 769-790 (2006)
  30. Structural analysis of cytochrome bc1 complexes: implications to the mechanism of function. Xia D, Esser L, Tang WK, Zhou F, Zhou Y, Yu L, Yu CA. Biochim Biophys Acta 1827 1278-1294 (2013)
  31. The role of Coenzyme Q in mitochondrial electron transport. Lenaz G, Fato R, Formiggini G, Genova ML. Mitochondrion 7 Suppl S8-33 (2007)
  32. Ischemia-reperfusion injury in the aged heart: role of mitochondria. Lesnefsky EJ, Hoppel CL. Arch Biochem Biophys 420 287-297 (2003)
  33. The cytochrome b6f complex at the crossroad of photosynthetic electron transport pathways. Tikhonov AN. Plant Physiol Biochem 81 163-183 (2014)
  34. Nuclear gene mutations as the cause of mitochondrial complex III deficiency. Fernández-Vizarra E, Zeviani M. Front Genet 6 134 (2015)
  35. The Q-cycle reviewed: How well does a monomeric mechanism of the bc(1) complex account for the function of a dimeric complex? Crofts AR, Holland JT, Victoria D, Kolling DR, Dikanov SA, Gilbreth R, Lhee S, Kuras R, Kuras MG. Biochim Biophys Acta 1777 1001-1019 (2008)
  36. Vitamin K2 in electron transport system: are enzymes involved in vitamin K2 biosynthesis promising drug targets? Kurosu M, Begari E. Molecules 15 1531-1553 (2010)
  37. Protein phosphorylation and redox sensing in chloroplast thylakoids. Vener AV, Ohad I, Andersson B. Curr Opin Plant Biol 1 217-223 (1998)
  38. Large scale domain movement in cytochrome bc(1): a new device for electron transfer in proteins. Darrouzet E, Moser CC, Dutton PL, Daldal F. Trends Biochem Sci 26 445-451 (2001)
  39. Mitochondria make a come back. Scheffler IE. Adv Drug Deliv Rev 49 3-26 (2001)
  40. Biogenesis of the cytochrome bc(1) complex and role of assembly factors. Smith PM, Fox JL, Winge DR. Biochim Biophys Acta 1817 276-286 (2012)
  41. Structure-function of the cytochrome b6f complex. Baniulis D, Yamashita E, Zhang H, Hasan SS, Cramer WA. Photochem Photobiol 84 1349-1358 (2008)
  42. Lipids in photosynthetic reaction centres: structural roles and functional holes. Jones MR. Prog Lipid Res 46 56-87 (2007)
  43. The recombinant expression systems for structure determination of eukaryotic membrane proteins. He Y, Wang K, Yan N. Protein Cell 5 658-672 (2014)
  44. Alternative FeS cluster ligands: tuning redox potentials and chemistry. Bak DW, Elliott SJ. Curr Opin Chem Biol 19 50-58 (2014)
  45. The oxidative phosphorylation (OXPHOS) system: nuclear genes and human genetic diseases. van den Heuvel L, Smeitink J. Bioessays 23 518-525 (2001)
  46. The role of mitochondria in cardiac development and protection. Pohjoismäki JL, Goffart S. Free Radic Biol Med 106 345-354 (2017)
  47. Anticancer drugs targeting the mitochondrial electron transport chain. Rohlena J, Dong LF, Ralph SJ, Neuzil J. Antioxid Redox Signal 15 2951-2974 (2011)
  48. Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions. Protasoni M, Zeviani M. Int J Mol Sci 22 E586 (2021)
  49. Proton transfer pathways and mechanism in bacterial reaction centers. Paddock ML, Feher G, Okamura MY. FEBS Lett 555 45-50 (2003)
  50. Structure and function of the cytochrome bc1 complex of mitochondria and photosynthetic bacteria. Crofts AR, Berry EA. Curr Opin Struct Biol 8 501-509 (1998)
  51. Active sites of transition-metal enzymes with a focus on nickel. Ermler U, Grabarse W, Shima S, Goubeaud M, Thauer RK. Curr Opin Struct Biol 8 749-758 (1998)
  52. Pathways to balance mitochondrial translation and protein import. Priesnitz C, Becker T. Genes Dev 32 1285-1296 (2018)
  53. The mitochondrial oxidative phosphorylation proteome of Chlamydomonas reinhardtii deduced from the Genome Sequencing Project. Cardol P, González-Halphen D, Reyes-Prieto A, Baurain D, Matagne RF, Remacle C. Plant Physiol 137 447-459 (2005)
  54. Mitochondrial processing peptidase: multiple-site recognition of precursor proteins. Ito A. Biochem Biophys Res Commun 265 611-616 (1999)
  55. New developments on the functions of coenzyme Q in mitochondria. Genova ML, Lenaz G. Biofactors 37 330-354 (2011)
  56. Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases. Meunier B, Fisher N, Ransac S, Mazat JP, Brasseur G. Biochim Biophys Acta 1827 1346-1361 (2013)
  57. Cytochrome b6f: structure for signalling and vectorial metabolism. Allen JF. Trends Plant Sci 9 130-137 (2004)
  58. Evolution of cytochrome bc complexes: from membrane-anchored dehydrogenases of ancient bacteria to triggers of apoptosis in vertebrates. Dibrova DV, Cherepanov DA, Galperin MY, Skulachev VP, Mulkidjanian AY. Biochim Biophys Acta 1827 1407-1427 (2013)
  59. Separation methods in the analysis of protein membrane complexes. Kashino Y. J Chromatogr B Analyt Technol Biomed Life Sci 797 191-216 (2003)
  60. Regulatory interactions in the dimeric cytochrome bc(1) complex: the advantages of being a twin. Covian R, Trumpower BL. Biochim Biophys Acta 1777 1079-1091 (2008)
  61. Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism. Korolnek T, Hamza I. Front Pharmacol 5 126 (2014)
  62. Chlamydomonas genetics, a tool for the study of bioenergetic pathways. Hippler M, Redding K, Rochaix JD. Biochim Biophys Acta 1367 1-62 (1998)
  63. Tuning microbial hosts for membrane protein production. Freigassner M, Pichler H, Glieder A. Microb Cell Fact 8 69 (2009)
  64. Molecular mechanisms of superoxide production by complex III: a bacterial versus human mitochondrial comparative case study. Lanciano P, Khalfaoui-Hassani B, Selamoglu N, Ghelli A, Rugolo M, Daldal F. Biochim Biophys Acta 1827 1332-1339 (2013)
  65. Why All the Fuss about Oxidative Phosphorylation (OXPHOS)? Xu Y, Xue D, Bankhead A, Neamati N. J Med Chem 63 14276-14307 (2020)
  66. Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities. Liu J, Zhu X, Kim SJ, Zhang W. Nat Prod Rep 33 1146-1165 (2016)
  67. Cytochrome bc complexes: a common core of structure and function surrounded by diversity in the outlying provinces. Smith JL, Zhang H, Yan J, Kurisu G, Cramer WA. Curr Opin Struct Biol 14 432-439 (2004)
  68. Toward understanding driving forces in membrane protein folding. Hong H. Arch Biochem Biophys 564 297-313 (2014)
  69. A critical appraisal of the mitochondrial coenzyme Q pool. Lenaz G. FEBS Lett 509 151-155 (2001)
  70. Electron transfer mechanisms. Beratan D, Skourtis S. Curr Opin Chem Biol 2 235-243 (1998)
  71. Succinate: quinone oxidoreductases: new insights from X-ray crystal structures. Lancaster CR, Kröger A. Biochim Biophys Acta 1459 422-431 (2000)
  72. The quinone-binding and catalytic site of complex II. Maklashina E, Cecchini G. Biochim Biophys Acta 1797 1877-1882 (2010)
  73. A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters. Yan N. J Mol Biol 429 2710-2725 (2017)
  74. How does cytochrome oxidase pump protons? Gennis RB. Proc Natl Acad Sci U S A 95 12747-12749 (1998)
  75. Mitochondrial production of reactive oxygen species. Grivennikova VG, Vinogradov AD. Biochemistry (Mosc) 78 1490-1511 (2013)
  76. Observations concerning the quinol oxidation site of the cytochrome bc1 complex. Berry EA, Huang LS. FEBS Lett 555 13-20 (2003)
  77. Proton translocation by the cytochrome bc1 complexes of phototrophic bacteria: introducing the activated Q-cycle. Mulkidjanian AY. Photochem Photobiol Sci 6 19-34 (2007)
  78. The chemistry and mechanics of ubihydroquinone oxidation at center P (Qo) of the cytochrome bc1 complex. Brandt U. Biochim Biophys Acta 1365 261-268 (1998)
  79. NADH dehydrogenases: from basic science to biomedicine. Yagi T, Seo BB, Di Bernardo S, Nakamaru-Ogiso E, Kao MC, Matsuno-Yagi A. J Bioenerg Biomembr 33 233-242 (2001)
  80. Catalytic Reactions and Energy Conservation in the Cytochrome bc1 and b6f Complexes of Energy-Transducing Membranes. Sarewicz M, Pintscher S, Pietras R, Borek A, Bujnowicz Ł, Hanke G, Cramer WA, Finazzi G, Osyczka A. Chem Rev 121 2020-2108 (2021)
  81. Proton translocation in the respiratory chain involving ubiquinone--a hypothetical semiquinone switch mechanism for complex I. Brandt U. Biofactors 9 95-101 (1999)
  82. Revealing various coupling of electron transfer and proton pumping in mitochondrial respiratory chain. Sun F, Zhou Q, Pang X, Xu Y, Rao Z. Curr Opin Struct Biol 23 526-538 (2013)
  83. Simple redox-linked proton-transfer design: new insights from structures of quinol-fumarate reductase. Ohnishi T, Moser CC, Page CC, Dutton PL, Yano T. Structure 8 R23-32 (2000)
  84. Structural basis for the mechanism of electron bifurcation at the quinol oxidation site of the cytochrome bc1 complex. Xia D, Esser L, Yu L, Yu CA. Photosynth Res 92 17-34 (2007)
  85. Structural organization of G-protein-coupled receptors. Lomize AL, Pogozheva ID, Mosberg HI. J Comput Aided Mol Des 13 325-353 (1999)
  86. Unanswered questions about the structure of cytochrome bc1 complexes. Berry EA, De Bari H, Huang LS. Biochim Biophys Acta 1827 1258-1277 (2013)
  87. Structure of the cytochrome b6f complex: new prosthetic groups, Q-space, and the 'hors d'oeuvres hypothesis' for assembly of the complex. Cramer WA, Yan J, Zhang H, Kurisu G, Smith JL. Photosynth Res 85 133-143 (2005)
  88. Analyzing your complexes: structure of the quinol-fumarate reductase respiratory complex. Iverson TM, Luna-Chavez C, Schröder I, Cecchini G, Rees DC. Curr Opin Struct Biol 10 448-455 (2000)
  89. Defects in mitochondrial respiratory complexes III and IV, and human pathologies. Borisov VB. Mol Aspects Med 23 385-412 (2002)
  90. Amazing structure of respirasome: unveiling the secrets of cell respiration. Guo R, Gu J, Wu M, Yang M. Protein Cell 7 854-865 (2016)
  91. Highlighting membrane protein structure and function: A celebration of the Protein Data Bank. Li F, Egea PF, Vecchio AJ, Asial I, Gupta M, Paulino J, Bajaj R, Dickinson MS, Ferguson-Miller S, Monk BC, Stroud RM. J Biol Chem 296 100557 (2021)
  92. Five decades of research on mitochondrial NADH-quinone oxidoreductase (complex I). Ohnishi T, Ohnishi ST, Salerno JC. Biol Chem 399 1249-1264 (2018)
  93. Insights from the structure of the yeast cytochrome bc1 complex: crystallization of membrane proteins with antibody fragments. Hunte C. FEBS Lett 504 126-132 (2001)
  94. Mitochondrial Dysfunctions: A Thread Sewing Together Alzheimer's Disease, Diabetes, and Obesity. Rigotto G, Basso E. Oxid Med Cell Longev 2019 7210892 (2019)
  95. The di-heme family of respiratory complex II enzymes. Lancaster CR. Biochim Biophys Acta 1827 679-687 (2013)
  96. Toward a characterization of the connecting module of complex I. Dupuis A, Prieur I, Lunardi J. J Bioenerg Biomembr 33 159-168 (2001)
  97. The photosynthetic apparatus of Rhodobacter sphaeroides. Verméglio A, Joliot P. Trends Microbiol 7 435-440 (1999)
  98. Wolinella succinogenes quinol:fumarate reductase and its comparison to E. coli succinate:quinone reductase. Lancaster CR. FEBS Lett 555 21-28 (2003)
  99. The cytochrome b(6)f complex: structural studies and comparison with the bc(1) complex. Breyton C. Biochim Biophys Acta 1459 467-474 (2000)
  100. Cystic fibrosis: a brief look at some highlights of a decade of research focused on elucidating and correcting the molecular basis of the disease. Ko YH, Pedersen PL. J Bioenerg Biomembr 33 513-521 (2001)
  101. Can All Major ROS Forming Sites of the Respiratory Chain Be Activated By High FADH2 /NADH Ratios?: Ancient evolutionary constraints determine mitochondrial ROS formation. Speijer D. Bioessays 41 e1800180 (2019)
  102. Crystal structures of all-alpha type membrane proteins. McLuskey K, Roszak AW, Zhu Y, Isaacs NW. Eur Biophys J 39 723-755 (2010)
  103. Succinate:quinone oxidoreductases--what can we learn from Wolinella succinogenes quinol:fumarate reductase? Lancaster CR. FEBS Lett 504 133-141 (2001)
  104. The mechanism of coupling between oxido-reduction and proton translocation in respiratory chain enzymes. Papa S, Capitanio G, Papa F. Biol Rev Camb Philos Soc 93 322-349 (2018)
  105. Recent advances in cytochrome bc(1): inter monomer electronic communication? Khalfaoui-Hassani B, Lanciano P, Lee DW, Darrouzet E, Daldal F. FEBS Lett 586 617-621 (2012)
  106. Water-soluble CoQ10 as A Promising Anti-aging Agent for Neurological Dysfunction in Brain Mitochondria. Takahashi M, Takahashi K. Antioxidants (Basel) 8 E61 (2019)
  107. Metals in membranes. Liang X, Campopiano DJ, Sadler PJ. Chem Soc Rev 36 968-992 (2007)
  108. Mitochondrial Supercomplexes: Physiological Organization and Dysregulation in Age-Related Neurodegenerative Disorders. Novack GV, Galeano P, Castaño EM, Morelli L. Front Endocrinol (Lausanne) 11 600 (2020)
  109. Structures of redox enzymes. Munro AW, Taylor P, Walkinshaw MD. Curr Opin Biotechnol 11 369-376 (2000)
  110. Design and use of photoactive ruthenium complexes to study electron transfer within cytochrome bc1 and from cytochrome bc1 to cytochrome c. Millett F, Havens J, Rajagukguk S, Durham B. Biochim Biophys Acta 1827 1309-1319 (2013)
  111. Electron transfer in proteins: theory, applications and future perspectives. Saen-Oon S, Lucas MF, Guallar V. Phys Chem Chem Phys 15 15271-15285 (2013)
  112. Evolution and unique bioenergetic mechanisms in oxygenic photosynthesis. Iverson TM. Curr Opin Chem Biol 10 91-100 (2006)
  113. Interplay between Mitochondrial Protein Import and Respiratory Complexes Assembly in Neuronal Health and Degeneration. Needs HI, Protasoni M, Henley JM, Prudent J, Collinson I, Pereira GC. Life (Basel) 11 432 (2021)
  114. Cooperative coupling and role of heme a in the proton pump of heme-copper oxidases. Papa S, Capitanio N, Villani G, Capitanio G, Bizzoca A, Palese LL, Carlino V, De Nitto E. Biochimie 80 821-836 (1998)
  115. Mitochondrial protein dysfunction in pathogenesis of neurological diseases. Wang L, Yang Z, He X, Pu S, Yang C, Wu Q, Zhou Z, Cen X, Zhao H. Front Mol Neurosci 15 974480 (2022)
  116. Research journey of respirasome. Wu M, Gu J, Zong S, Guo R, Liu T, Yang M. Protein Cell 11 318-338 (2020)
  117. Traditional and novel tools to probe the mitochondrial metabolism in health and disease. Zhang Y, Avalos JL. Wiley Interdiscip Rev Syst Biol Med 9 (2017)
  118. Large unit cells and cellular mechanics. Grimes JM, Stuart DI. Nat Struct Biol 5 Suppl 630-634 (1998)
  119. Recent Insights into the Structure and Function of Mycobacterial Membrane Proteins Facilitated by Cryo-EM. Bendre AD, Peters PJ, Kumar J. J Membr Biol 254 321-341 (2021)
  120. Antimalarial Inhibitors Targeting Epigenetics or Mitochondria in Plasmodium falciparum: Recent Survey upon Synthesis and Biological Evaluation of Potential Drugs against Malaria. Koumpoura CL, Robert A, Athanassopoulos CM, Baltas M. Molecules 26 5711 (2021)
  121. Assembly of the Multi-Subunit Cytochrome bc1 Complex in the Yeast Saccharomyces cerevisiae. Zara V, De Blasi G, Ferramosca A. Int J Mol Sci 23 10537 (2022)
  122. Rieske iron-sulfur protein of the cytochrome bc(1) complex: a potential target for fungicide discovery. Yang WC, Li H, Wang F, Zhu XL, Yang GF. Chembiochem 13 1542-1551 (2012)
  123. Bcs1, a novel target for fungicide. Zhan J, Xia D. Front Chem 11 1146753 (2023)
  124. Current Developments in Native Nanometric Discoidal Membrane Bilayer Formed by Amphipathic Polymers. Esmaili M, Eldeeb MA, Moosavi-Movahedi AA. Nanomaterials (Basel) 11 1771 (2021)
  125. Energy transduction function of the quinone reactions in cytochrome bc complexes. Cramer WA, Soriano GM. Biofactors 9 81-86 (1999)

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  1. Structure of bacteriorhodopsin at 1.55 A resolution. Luecke H, Schobert B, Richter HT, Cartailler JP, Lanyi JK. J Mol Biol 291 899-911 (1999)
  2. Electron transfer by domain movement in cytochrome bc1. Zhang Z, Huang L, Shulmeister VM, Chi YI, Kim KK, Hung LW, Crofts AR, Berry EA, Kim SH. Nature 392 677-684 (1998)
  3. Membranes are more mosaic than fluid. Engelman DM. Nature 438 578-580 (2005)
  4. Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. Feng J, Bussière F, Hekimi S. Dev Cell 1 633-644 (2001)
  5. Crystal structure of mitochondrial respiratory membrane protein complex II. Sun F, Huo X, Zhai Y, Wang A, Xu J, Su D, Bartlam M, Rao Z. Cell 121 1043-1057 (2005)
  6. An atypical haem in the cytochrome b(6)f complex. Stroebel D, Choquet Y, Popot JL, Picot D. Nature 426 413-418 (2003)
  7. Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Hunte C, Koepke J, Lange C, Rossmanith T, Michel H. Structure 8 669-684 (2000)
  8. Specific roles of protein-phospholipid interactions in the yeast cytochrome bc1 complex structure. Lange C, Nett JH, Trumpower BL, Hunte C. EMBO J 20 6591-6600 (2001)
  9. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Tzung SP, Kim KM, Basañez G, Giedt CD, Simon J, Zimmerberg J, Zhang KY, Hockenbery DM. Nat Cell Biol 3 183-191 (2001)
  10. Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. James AM, Cochemé HM, Smith RA, Murphy MP. J Biol Chem 280 21295-21312 (2005)
  11. Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice. Grigorieff N. J Mol Biol 277 1033-1046 (1998)
  12. Heterotachy, an important process of protein evolution. Lopez P, Casane D, Philippe H. Mol Biol Evol 19 1-7 (2002)
  13. Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A. Bertero MG, Rothery RA, Palak M, Hou C, Lim D, Blasco F, Weiner JH, Strynadka NC. Nat Struct Biol 10 681-687 (2003)
  14. Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c. Lange C, Hunte C. Proc Natl Acad Sci U S A 99 2800-2805 (2002)
  15. Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites. Srivastava IK, Morrisey JM, Darrouzet E, Daldal F, Vaidya AB. Mol Microbiol 33 704-711 (1999)
  16. Structure of fumarate reductase from Wolinella succinogenes at 2.2 A resolution. Lancaster CR, Kröger A, Auer M, Michel H. Nature 402 377-385 (1999)
  17. The Qo site of cytochrome b6f complexes controls the activation of the LHCII kinase. Zito F, Finazzi G, Delosme R, Nitschke W, Picot D, Wollman FA. EMBO J 18 2961-2969 (1999)
  18. Binding of the respiratory chain inhibitor antimycin to the mitochondrial bc1 complex: a new crystal structure reveals an altered intramolecular hydrogen-bonding pattern. Huang LS, Cobessi D, Tung EY, Berry EA. J Mol Biol 351 573-597 (2005)
  19. Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Taylor AB, Smith BS, Kitada S, Kojima K, Miyaura H, Otwinowski Z, Ito A, Deisenhofer J. Structure 9 615-625 (2001)
  20. Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. Esser L, Quinn B, Li YF, Zhang M, Elberry M, Yu L, Yu CA, Xia D. J Mol Biol 341 281-302 (2004)
  21. A mechanism for the synergistic antimalarial action of atovaquone and proguanil. Srivastava IK, Vaidya AB. Antimicrob Agents Chemother 43 1334-1339 (1999)
  22. Inhibitor binding changes domain mobility in the iron-sulfur protein of the mitochondrial bc1 complex from bovine heart. Kim H, Xia D, Yu CA, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofer J. Proc Natl Acad Sci U S A 95 8026-8033 (1998)
  23. Reversible redox energy coupling in electron transfer chains. Osyczka A, Moser CC, Daldal F, Dutton PL. Nature 427 607-612 (2004)
  24. A century of mitochondrial research: achievements and perspectives. Scheffler IE. Mitochondrion 1 3-31 (2001)
  25. Supramolecular organization of the photosynthetic apparatus of Rhodobacter sphaeroides. Jungas C, Ranck JL, Rigaud JL, Joliot P, Verméglio A. EMBO J 18 534-542 (1999)
  26. X-Ray Structure of Rhodobacter Capsulatus Cytochrome bc (1): Comparison with its Mitochondrial and Chloroplast Counterparts. Berry EA, Huang LS, Saechao LK, Pon NG, Valkova-Valchanova M, Daldal F. Photosynth Res 81 251-275 (2004)
  27. Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. Zhang J, Frerman FE, Kim JJ. Proc Natl Acad Sci U S A 103 16212-16217 (2006)
  28. Structural details of an interaction between cardiolipin and an integral membrane protein. McAuley KE, Fyfe PK, Ridge JP, Isaacs NW, Cogdell RJ, Jones MR. Proc Natl Acad Sci U S A 96 14706-14711 (1999)
  29. Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress. Rabbani N, Thornalley PJ. Biochem Soc Trans 36 1045-1050 (2008)
  30. Structure of the yeast cytochrome bc1 complex with a hydroxyquinone anion Qo site inhibitor bound. Palsdottir H, Lojero CG, Trumpower BL, Hunte C. J Biol Chem 278 31303-31311 (2003)
  31. Thermostabilization of the neurotensin receptor NTS1. Shibata Y, White JF, Serrano-Vega MJ, Magnani F, Aloia AL, Grisshammer R, Tate CG. J Mol Biol 390 262-277 (2009)
  32. Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB. Abrahams KA, Cox JA, Spivey VL, Loman NJ, Pallen MJ, Constantinidou C, Fernández R, Alemparte C, Remuiñán MJ, Barros D, Ballell L, Besra GS. PLoS One 7 e52951 (2012)
  33. Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria. Leissring MA, Farris W, Wu X, Christodoulou DC, Haigis MC, Guarente L, Selkoe DJ. Biochem J 383 439-446 (2004)
  34. Aging decreases electron transport complex III activity in heart interfibrillar mitochondria by alteration of the cytochrome c binding site. Lesnefsky EJ, Gudz TI, Moghaddas S, Migita CT, Ikeda-Saito M, Turkaly PJ, Hoppel CL. J Mol Cell Cardiol 33 37-47 (2001)
  35. Dark-interval relaxation kinetics (DIRK) of absorbance changes as a quantitative probe of steady-state electron transfer. Sacksteder CA, Kramer DM. Photosynth Res 66 145-158 (2000)
  36. An out-of-frame cytochrome b gene deletion from a patient with parkinsonism is associated with impaired complex III assembly and an increase in free radical production. Rana M, de Coo I, Diaz F, Smeets H, Moraes CT. Ann Neurol 48 774-781 (2000)
  37. Refolding of Escherichia coli produced membrane protein inclusion bodies immobilised by nickel chelating chromatography. Rogl H, Kosemund K, Kühlbrandt W, Collinson I. FEBS Lett 432 21-26 (1998)
  38. A motif for quinone binding sites in respiratory and photosynthetic systems. Fisher N, Rich PR. J Mol Biol 296 1153-1162 (2000)
  39. Expression of G protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors. Ishihara G, Goto M, Saeki M, Ito K, Hori T, Kigawa T, Shirouzu M, Yokoyama S. Protein Expr Purif 41 27-37 (2005)
  40. Watching the photosynthetic apparatus in native membranes. Scheuring S, Sturgis JN, Prima V, Bernadac A, Lévy D, Rigaud JL. Proc Natl Acad Sci U S A 101 11293-11297 (2004)
  41. Structural analysis of atovaquone-inhibited cytochrome bc1 complex reveals the molecular basis of antimalarial drug action. Birth D, Kao WC, Hunte C. Nat Commun 5 4029 (2014)
  42. Phosphatidylglycerol is involved in the dimerization of photosystem II. Kruse O, Hankamer B, Konczak C, Gerle C, Morris E, Radunz A, Schmid GH, Barber J. J Biol Chem 275 6509-6514 (2000)
  43. The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target. Paetzel M, Dalbey RE, Strynadka NC. Pharmacol Ther 87 27-49 (2000)
  44. Biological identity and diversity in photosynthesis and respiration: structure of the lumen-side domain of the chloroplast Rieske protein. Carrell CJ, Zhang H, Cramer WA, Smith JL. Structure 5 1613-1625 (1997)
  45. Pathways for proton release during ubihydroquinone oxidation by the bc(1) complex. Crofts AR, Hong S, Ugulava N, Barquera B, Gennis R, Guergova-Kuras M, Berry EA. Proc Natl Acad Sci U S A 96 10021-10026 (1999)
  46. Conformational gating of the electron transfer reaction QA-.QB --> QAQB-. in bacterial reaction centers of Rhodobacter sphaeroides determined by a driving force assay. Graige MS, Feher G, Okamura MY. Proc Natl Acad Sci U S A 95 11679-11684 (1998)
  47. GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model. Hilgemann DW, Lu CC. J Gen Physiol 114 459-475 (1999)
  48. Surface-modulated motion switch: capture and release of iron-sulfur protein in the cytochrome bc1 complex. Esser L, Gong X, Yang S, Yu L, Yu CA, Xia D. Proc Natl Acad Sci U S A 103 13045-13050 (2006)
  49. Uncovering the [2Fe2S] domain movement in cytochrome bc1 and its implications for energy conversion. Darrouzet E, Valkova-Valchanova M, Moser CC, Dutton PL, Daldal F. Proc Natl Acad Sci U S A 97 4567-4572 (2000)
  50. Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria. Moghaddas S, Hoppel CL, Lesnefsky EJ. Arch Biochem Biophys 414 59-66 (2003)
  51. Steered molecular dynamics simulation of the Rieske subunit motion in the cytochrome bc(1) complex. Izrailev S, Crofts AR, Berry EA, Schulten K. Biophys J 77 1753-1768 (1999)
  52. Transmembrane heme delivery systems. Goldman BS, Beck DL, Monika EM, Kranz RG. Proc Natl Acad Sci U S A 95 5003-5008 (1998)
  53. Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria. Hikosaka K, Watanabe Y, Tsuji N, Kita K, Kishine H, Arisue N, Palacpac NM, Kawazu S, Sawai H, Horii T, Igarashi I, Tanabe K. Mol Biol Evol 27 1107-1116 (2010)
  54. Biochemical dissection of the mitochondrial proteome from Arabidopsis thaliana by three-dimensional gel electrophoresis. Werhahn W, Braun HP. Electrophoresis 23 640-646 (2002)
  55. Cytochrome b(6)f mutation specifically affects thermal dissipation of absorbed light energy in Arabidopsis. Munekage Y, Takeda S, Endo T, Jahns P, Hashimoto T, Shikanai T. Plant J 28 351-359 (2001)
  56. Lipidic Cubic Phases: New Matrices for the Three-Dimensional Crystallization of Membrane Proteins. Rummel G, Hardmeyer A, Widmer C, Chiu ML, Nollert P, Locher KP, Pedruzzi I, Landau EM, Rosenbusch JP. J Struct Biol 121 82-91 (1998)
  57. Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. Jung HJ, Shim JS, Lee J, Song YM, Park KC, Choi SH, Kim ND, Yoon JH, Mungai PT, Schumacker PT, Kwon HJ. J Biol Chem 285 11584-11595 (2010)
  58. The 49-kDa subunit of NADH-ubiquinone oxidoreductase (Complex I) is involved in the binding of piericidin and rotenone, two quinone-related inhibitors. Darrouzet E, Issartel JP, Lunardi J, Dupuis A. FEBS Lett 431 34-38 (1998)
  59. The photosynthetic apparatus of Rhodopseudomonas palustris: structures and organization. Scheuring S, Gonçalves RP, Prima V, Sturgis JN. J Mol Biol 358 83-96 (2006)
  60. Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site. Iverson TM, Luna-Chavez C, Croal LR, Cecchini G, Rees DC. J Biol Chem 277 16124-16130 (2002)
  61. Electronic connection between the quinone and cytochrome C redox pools and its role in regulation of mitochondrial electron transport and redox signaling. Sarewicz M, Osyczka A. Physiol Rev 95 219-243 (2015)
  62. Determination of the binding sites of the proton transfer inhibitors Cd2+ and Zn2+ in bacterial reaction centers. Axelrod HL, Abresch EC, Paddock ML, Okamura MY, Feher G. Proc Natl Acad Sci U S A 97 1542-1547 (2000)
  63. Importance of the alternative oxidase (AOX) pathway in regulating cellular redox and ROS homeostasis to optimize photosynthesis during restriction of the cytochrome oxidase pathway in Arabidopsis thaliana. Vishwakarma A, Tetali SD, Selinski J, Scheibe R, Padmasree K. Ann Bot 116 555-569 (2015)
  64. Heme cytotoxicity and the pathogenesis of immune-mediated inflammatory diseases. Larsen R, Gouveia Z, Soares MP, Gozzelino R. Front Pharmacol 3 77 (2012)
  65. Structure of the cytochrome b6f complex: quinone analogue inhibitors as ligands of heme cn. Yamashita E, Zhang H, Cramer WA. J Mol Biol 370 39-52 (2007)
  66. Electron Flow through Proteins. Gray HB, Winkler JR. Chem Phys Lett 483 1-9 (2009)
  67. Structure of the dimeric PufX-containing core complex of Rhodobacter blasticus by in situ atomic force microscopy. Scheuring S, Busselez J, Lévy D. J Biol Chem 280 1426-1431 (2005)
  68. The long-range supraorganization of the bacterial photosynthetic unit: A key role for PufX. Frese RN, Olsen JD, Branvall R, Westerhuis WH, Hunter CN, van Grondelle R. Proc Natl Acad Sci U S A 97 5197-5202 (2000)
  69. Rows of ATP synthase dimers in native mitochondrial inner membranes. Buzhynskyy N, Sens P, Prima V, Sturgis JN, Scheuring S. Biophys J 93 2870-2876 (2007)
  70. Simultaneous reduction of iron-sulfur protein and cytochrome b(L) during ubiquinol oxidation in cytochrome bc(1) complex. Zhu J, Egawa T, Yeh SR, Yu L, Yu CA. Proc Natl Acad Sci U S A 104 4864-4869 (2007)
  71. Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Ulanovskaya OA, Janjic J, Suzuki M, Sabharwal SS, Schumacker PT, Kron SJ, Kozmin SA. Nat Chem Biol 4 418-424 (2008)
  72. Absorption and CD spectroscopy and modeling of various LH2 complexes from purple bacteria. Georgakopoulou S, Frese RN, Johnson E, Koolhaas C, Cogdell RJ, van Grondelle R, van der Zwan G. Biophys J 82 2184-2197 (2002)
  73. A specific c-type cytochrome maturation system is required for oxygenic photosynthesis. Kuras R, Saint-Marcoux D, Wollman FA, de Vitry C. Proc Natl Acad Sci U S A 104 9906-9910 (2007)
  74. Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1. Capper MJ, O'Neill PM, Fisher N, Strange RW, Moss D, Ward SA, Berry NG, Lawrenson AS, Hasnain SS, Biagini GA, Antonyuk SV. Proc Natl Acad Sci U S A 112 755-760 (2015)
  75. Septo-optic dysplasia associated with a new mitochondrial cytochrome b mutation. Schuelke M, Krude H, Finckh B, Mayatepek E, Janssen A, Schmelz M, Trefz F, Trijbels F, Smeitink J. Ann Neurol 51 388-392 (2002)
  76. The LYR protein Mzm1 functions in the insertion of the Rieske Fe/S protein in yeast mitochondria. Atkinson A, Smith P, Fox JL, Cui TZ, Khalimonchuk O, Winge DR. Mol Cell Biol 31 3988-3996 (2011)
  77. Identification and characterization of cytochrome bc(1) subcomplexes in mitochondria from yeast with single and double deletions of genes encoding cytochrome bc(1) subunits. Zara V, Conte L, Trumpower BL. FEBS J 274 4526-4539 (2007)
  78. mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III. Gusdon AM, Votyakova TV, Mathews CE. J Biol Chem 283 10690-10697 (2008)
  79. Crystallographic location of two Zn(2+)-binding sites in the avian cytochrome bc(1) complex. Berry EA, Zhang Z, Bellamy HD, Huang L. Biochim Biophys Acta 1459 440-448 (2000)
  80. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Ma X, Jin M, Cai Y, Xia H, Long K, Liu J, Yu Q, Yuan J. Chem Biol 18 1474-1481 (2011)
  81. The Q-cycle - A Personal Perspective. Crofts AR. Photosynth Res 80 223-243 (2004)
  82. Atovaquone resistance in malaria parasites. Vaidya AB, Mather MW. Drug Resist Updat 3 283-287 (2000)
  83. Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex. Siregar JE, Kurisu G, Kobayashi T, Matsuzaki M, Sakamoto K, Mi-ichi F, Watanabe Y, Hirai M, Matsuoka H, Syafruddin D, Marzuki S, Kita K. Parasitol Int 64 295-300 (2015)
  84. Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters. Kolling DJ, Brunzelle JS, Lhee S, Crofts AR, Nair SK. Structure 15 29-38 (2007)
  85. Cellular pathophysiological consequences of BCS1L mutations in mitochondrial complex III enzyme deficiency. Morán M, Marín-Buera L, Gil-Borlado MC, Rivera H, Blázquez A, Seneca S, Vázquez-López M, Arenas J, Martín MA, Ugalde C. Hum Mutat 31 930-941 (2010)
  86. The Rieske protein from Paracoccus denitrificans is inserted into the cytoplasmic membrane by the twin-arginine translocase. Bachmann J, Bauer B, Zwicker K, Ludwig B, Anderka O. FEBS J 273 4817-4830 (2006)
  87. The energy landscape for ubihydroquinone oxidation at the Q(o) site of the bc(1) complex in Rhodobacter sphaeroides. Hong S, Ugulava N, Guergova-Kuras M, Crofts AR. J Biol Chem 274 33931-33944 (1999)
  88. Alternative Oxidase Isoforms Are Differentially Activated by Tricarboxylic Acid Cycle Intermediates. Selinski J, Hartmann A, Deckers-Hebestreit G, Day DA, Whelan J, Scheibe R. Plant Physiol 176 1423-1432 (2018)
  89. Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms. Sazanov LA, Walker JE. J Mol Biol 302 455-464 (2000)
  90. Late-stage maturation of the Rieske Fe/S protein: Mzm1 stabilizes Rip1 but does not facilitate its translocation by the AAA ATPase Bcs1. Cui TZ, Smith PM, Fox JL, Khalimonchuk O, Winge DR. Mol Cell Biol 32 4400-4409 (2012)
  91. Mutations in the mitochondrial cytochrome b of Tetranychus urticae Koch (Acari: Tetranychidae) confer cross-resistance between bifenazate and acequinocyl. Van Nieuwenhuyse P, Van Leeuwen T, Khajehali J, Vanholme B, Tirry L. Pest Manag Sci 65 404-412 (2009)
  92. Direct demonstration of half-of-the-sites reactivity in the dimeric cytochrome bc1 complex: enzyme with one inactive monomer is fully active but unable to activate the second ubiquinol oxidation site in response to ligand binding at the ubiquinone reduction site. Castellani M, Covian R, Kleinschroth T, Anderka O, Ludwig B, Trumpower BL. J Biol Chem 285 502-510 (2010)
  93. Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane. Zara V, Conte L, Trumpower BL. FEBS J 276 1900-1914 (2009)
  94. Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex. Yan J, Kurisu G, Cramer WA. Proc Natl Acad Sci U S A 103 69-74 (2006)
  95. Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis elegans. Suthammarak W, Morgan PG, Sedensky MM. J Biol Chem 285 40724-40731 (2010)
  96. Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. McCord LA, Liang WG, Dowdell E, Kalas V, Hoey RJ, Koide A, Koide S, Tang WJ. Proc Natl Acad Sci U S A 110 13827-13832 (2013)
  97. D(n)-symmetrical tertiary templates for the design of tubular proteins. North B, Summa CM, Ghirlanda G, DeGrado WF. J Mol Biol 311 1081-1090 (2001)
  98. The insecticide target in the PSST subunit of complex I. Schuler F, Casida JE. Pest Manag Sci 57 932-940 (2001)
  99. Unusual location of a mitochondrial gene. Subunit III of cytochrome C oxidase is encoded in the nucleus of Chlamydomonad algae. Pérez-Martínez X, Vazquez-Acevedo M, Tolkunova E, Funes S, Claros MG, Davidson E, King MP, González-Halphen D. J Biol Chem 275 30144-30152 (2000)
  100. A spectroscopic method for observing the domain movement of the Rieske iron-sulfur protein. Brugna M, Rodgers S, Schricker A, Montoya G, Kazmeier M, Nitschke W, Sinning I. Proc Natl Acad Sci U S A 97 2069-2074 (2000)
  101. Structural model and excitonic properties of the dimeric RC-LH1-PufX complex from Rhodobacter sphaeroides. Sener M, Hsin J, Trabuco LG, Villa E, Qian P, Hunter CN, Schulten K. Chem Phys 357 188-197 (2009)
  102. The organization of LH2 complexes in membranes from Rhodobacter sphaeroides. Olsen JD, Tucker JD, Timney JA, Qian P, Vassilev C, Hunter CN. J Biol Chem 283 30772-30779 (2008)
  103. Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b. Zara V, Palmisano I, Conte L, Trumpower BL. Eur J Biochem 271 1209-1218 (2004)
  104. Intermonomer electron transfer between the low-potential b hemes of cytochrome bc₁. Lanciano P, Lee DW, Yang H, Darrouzet E, Daldal F. Biochemistry 50 1651-1663 (2011)
  105. Single point mutation in the Rieske iron-sulfur subunit of cytochrome b6/f leads to an altered pH dependence of plastoquinol oxidation in Arabidopsis. Jahns P, Graf M, Munekage Y, Shikanai T. FEBS Lett 519 99-102 (2002)
  106. Across membrane communication between the Q(o) and Q(i) active sites of cytochrome bc(1). Cooley JW, Lee DW, Daldal F. Biochemistry 48 1888-1899 (2009)
  107. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, Glynne RJ, Supek F. PLoS Pathog 11 e1005058 (2015)
  108. A reductase/isomerase subunit of mitochondrial NADH:ubiquinone oxidoreductase (complex I) carries an NADPH and is involved in the biogenesis of the complex. Schulte U, Haupt V, Abelmann A, Fecke W, Brors B, Rasmussen T, Friedrich T, Weiss H. J Mol Biol 292 569-580 (1999)
  109. Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants. Maldonado M, Guo F, Letts JA. Elife 10 e62047 (2021)
  110. The single chlorophyll a molecule in the cytochrome b6f complex: unusual optical properties protect the complex against singlet oxygen. Dashdorj N, Zhang H, Kim H, Yan J, Cramer WA, Savikhin S. Biophys J 88 4178-4187 (2005)
  111. Topology determination and functional analysis of the Escherichia coli TatC protein. Gouffi K, Santini CL, Wu LF. FEBS Lett 525 65-70 (2002)
  112. Cryo-EM structure of the spinach cytochrome b6 f complex at 3.6 Å resolution. Malone LA, Qian P, Mayneord GE, Hitchcock A, Farmer DA, Thompson RF, Swainsbury DJK, Ranson NA, Hunter CN, Johnson MP. Nature 575 535-539 (2019)
  113. Exploration of ligands to the Qi site semiquinone in the bc1 complex using high-resolution EPR. Kolling DR, Samoilova RI, Holland JT, Berry EA, Dikanov SA, Crofts AR. J Biol Chem 278 39747-39754 (2003)
  114. The Qo-site inhibitor DBMIB favours the proximal position of the chloroplast Rieske protein and induces a pK-shift of the redox-linked proton. Schoepp B, Brugna M, Riedel A, Nitschke W, Kramer DM. FEBS Lett 450 245-250 (1999)
  115. Atomic force microscopy of the bacterial photosynthetic apparatus: plain pictures of an elaborate machinery. Scheuring S, Sturgis JN. Photosynth Res 102 197-211 (2009)
  116. Caspase cleavage of cytochrome c1 disrupts mitochondrial function and enhances cytochrome c release. Zhu Y, Li M, Wang X, Jin H, Liu S, Xu J, Chen Q. Cell Res 22 127-141 (2012)
  117. Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex. Maclean AE, Bridges HR, Silva MF, Ding S, Ovciarikova J, Hirst J, Sheiner L. PLoS Pathog 17 e1009301 (2021)
  118. Fluorescence and absorption spectroscopy of the weakly fluorescent chlorophyll a in cytochrome b6f of Synechocystis PCC6803. Peterman EJ, Wenk SO, Pullerits T, Pâlsson LO, van Grondelle R, Dekker JP, Rögner M, van Amerongen H. Biophys J 75 389-398 (1998)
  119. Photosynthetic vesicle architecture and constraints on efficient energy harvesting. Sener M, Strümpfer J, Timney JA, Freiberg A, Hunter CN, Schulten K. Biophys J 99 67-75 (2010)
  120. Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides. Francia F, Wang J, Zischka H, Venturoli G, Oesterhelt D. Eur J Biochem 269 1877-1885 (2002)
  121. Structural basis of functions of the mitochondrial cytochrome bc1 complex. Yu CA, Xia D, Kim H, Deisenhofer J, Zhang L, Kachurin AM, Yu L. Biochim Biophys Acta 1365 151-158 (1998)
  122. The Cytochrome bc (1) Complex and its Homologue the b (6) f Complex: Similarities and Differences. Darrouzet E, Cooley JW, Daldal F. Photosynth Res 79 25-44 (2004)
  123. Anti-cooperative oxidation of ubiquinol by the yeast cytochrome bc1 complex. Covian R, Gutierrez-Cirlos EB, Trumpower BL. J Biol Chem 279 15040-15049 (2004)
  124. Determining Rieske cluster reduction potentials. Brown EN, Friemann R, Karlsson A, Parales JV, Couture MM, Eltis LD, Ramaswamy S. J Biol Inorg Chem 13 1301-1313 (2008)
  125. Analysis of the nucleus-encoded and chloroplast-targeted rieske protein by classic and site-directed mutagenesis of Chlamydomonas. de Vitry C, Finazzi G, Baymann F, Kallas T. Plant Cell 11 2031-2044 (1999)
  126. Conformational relaxation and water penetration coupled to ionization of internal groups in proteins. Damjanović A, Brooks BR, García-Moreno B. J Phys Chem A 115 4042-4053 (2011)
  127. Magnetic interactions sense changes in distance between heme b(L) and the iron-sulfur cluster in cytochrome bc(1). Sarewicz M, Dutka M, Froncisz W, Osyczka A. Biochemistry 48 5708-5720 (2009)
  128. Photoinduced electron transfer between the Rieske iron-sulfur protein and cytochrome c(1) in the Rhodobacter sphaeroides cytochrome bc(1) complex. Effects of pH, temperature, and driving force. Engstrom G, Xiao K, Yu CA, Yu L, Durham B, Millett F. J Biol Chem 277 31072-31078 (2002)
  129. Amino acid sequence, crystallization and structure determination of reduced and oxidized cytochrome c6 from the green alga Scenedesmus obliquus. Schnackenberg J, Than ME, Mann K, Wiegand G, Huber R, Reuter W. J Mol Biol 290 1019-1030 (1999)
  130. Intermonomer electron transfer in the bc1 complex dimer is controlled by the energized state and by impaired electron transfer between low and high potential hemes. Shinkarev VP, Wraight CA. FEBS Lett 581 1535-1541 (2007)
  131. Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. Dingley SD, Polyak E, Ostrovsky J, Srinivasan S, Lee I, Rosenfeld AB, Tsukikawa M, Xiao R, Selak MA, Coon JJ, Hebert AS, Grimsrud PA, Kwon YJ, Pagliarini DJ, Gai X, Schurr TG, Hüttemann M, Nakamaru-Ogiso E, Falk MJ. J Mol Biol 426 2199-2216 (2014)
  132. Modulation of the respiratory supercomplexes in yeast: enhanced formation of cytochrome oxidase increases the stability and abundance of respiratory supercomplexes. Cui TZ, Conte A, Fox JL, Zara V, Winge DR. J Biol Chem 289 6133-6141 (2014)
  133. Rapid electron transfer between monomers when the cytochrome bc1 complex dimer is reduced through center N. Covian R, Trumpower BL. J Biol Chem 280 22732-22740 (2005)
  134. Structures of Tetrahymena's respiratory chain reveal the diversity of eukaryotic core metabolism. Zhou L, Maldonado M, Padavannil A, Guo F, Letts JA. Science 376 831-839 (2022)
  135. Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein. Tang WK, Borgnia MJ, Hsu AL, Esser L, Fox T, de Val N, Xia D. Nat Struct Mol Biol 27 202-209 (2020)
  136. Differential Expression of Genes that Control Respiration Contribute to Thermal Adaptation in Redband Trout (Oncorhynchus mykiss gairdneri). Garvin MR, Thorgaard GH, Narum SR. Genome Biol Evol 7 1404-1414 (2015)
  137. Dynamic interaction of plastocyanin with the cytochrome bf complex. Illerhaus J, Altschmied L, Reichert J, Zak E, Herrmann RG, Haehnel W. J Biol Chem 275 17590-17595 (2000)
  138. Mutagenesis and computer modelling approach to study determinants for recognition of signal peptides by the mitochondrial processing peptidase. Zhang XP, Sjöling S, Tanudji M, Somogyi L, Andreu D, Eriksson LE, Gräslund A, Whelan J, Glaser E. Plant J 27 427-438 (2001)
  139. Mutations in the membrane anchor of yeast cytochrome c1 compensate for the absence of Oxa1p and generate carbonate-extractable forms of cytochrome c1. Hamel P, Lemaire C, Bonnefoy N, Brivet-Chevillotte P, Dujardin G. Genetics 150 601-611 (1998)
  140. Pathogenic mutations in the 5' untranslated region of BCS1L mRNA in mitochondrial complex III deficiency. Gil-Borlado MC, González-Hoyuela M, Blázquez A, García-Silva MT, Gabaldón T, Manzanares J, Vara J, Martín MA, Seneca S, Arenas J, Ugalde C. Mitochondrion 9 299-305 (2009)
  141. Zinc inhibition of bacterial cytochrome bc(1) reveals the role of cytochrome b E295 in proton release at the Q(o) site. Lee DW, El Khoury Y, Francia F, Zambelli B, Ciurli S, Venturoli G, Hellwig P, Daldal F. Biochemistry 50 4263-4272 (2011)
  142. Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain. Markevich NI, Hoek JB. Biochim Biophys Acta 1847 656-679 (2015)
  143. The oxidized subunit B8 from human complex I adopts a thioredoxin fold. Brockmann C, Diehl A, Rehbein K, Strauss H, Schmieder P, Korn B, Kühne R, Oschkinat H. Structure 12 1645-1654 (2004)
  144. The projection structure of the low temperature K intermediate of the bacteriorhodopsin photocycle determined by electron diffraction. Bullough PA, Henderson R. J Mol Biol 286 1663-1671 (1999)
  145. Analysis of Posttranslational Activation of Alternative Oxidase Isoforms. Selinski J, Hartmann A, Kordes A, Deckers-Hebestreit G, Whelan J, Scheibe R. Plant Physiol 174 2113-2127 (2017)
  146. Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition. Nalvarte I, Damdimopoulos AE, Spyrou G. Free Radic Biol Med 36 1270-1278 (2004)
  147. Impact of the mitochondrial genetic background in complex III deficiency. Gil Borlado MC, Moreno Lastres D, Gonzalez Hoyuela M, Moran M, Blazquez A, Pello R, Marin Buera L, Gabaldon T, Garcia Peñas JJ, Martín MA, Arenas J, Ugalde C. PLoS One 5 e12801 (2010)
  148. Increased variation in mtDNA in patients with familial sensorineural hearing impairment. Lehtonen MS, Moilanen JS, Majamaa K. Hum Genet 113 220-227 (2003)
  149. Phylogenetic analysis of Babesia species in China based on Cytochrome b (COB) gene. Tian Z, Luo J, Zheng J, Xie J, Shen H, Yin H, Luo J, Tian M, Yuan X, Wang F, Liu G. Infect Genet Evol 13 36-40 (2013)
  150. Quinol oxidation by c-type cytochromes: structural characterization of the menaquinol binding site of NrfHA. Rodrigues ML, Scott KA, Sansom MS, Pereira IA, Archer M. J Mol Biol 381 341-350 (2008)
  151. The cytochrome bc1 complex of Rhodobacter capsulatus: ubiquinol oxidation in a dimeric Q-cycle? Gopta OA, Feniouk BA, Junge W, Mulkidjanian AY. FEBS Lett 431 291-296 (1998)
  152. Crystal structure of the bromide-bound D85S mutant of bacteriorhodopsin: principles of ion pumping. Facciotti MT, Cheung VS, Nguyen D, Rouhani S, Glaeser RM. Biophys J 85 451-458 (2003)
  153. Identification of ubiquinol binding motifs at the Qo-site of the cytochrome bc1 complex. Barragan AM, Crofts AR, Schulten K, Solov'yov IA. J Phys Chem B 119 433-447 (2015)
  154. Modifications of protein environment of the [2Fe-2S] cluster of the bc1 complex: effects on the biophysical properties of the rieske iron-sulfur protein and on the kinetics of the complex. Lhee S, Kolling DR, Nair SK, Dikanov SA, Crofts AR. J Biol Chem 285 9233-9248 (2010)
  155. Molecular basis of substrate recognition and degradation by human presequence protease. King JV, Liang WG, Scherpelz KP, Schilling AB, Meredith SC, Tang WJ. Structure 22 996-1007 (2014)
  156. The molecular evolution of the Qo motif. Kao WC, Hunte C. Genome Biol Evol 6 1894-1910 (2014)
  157. The role of molecular modeling in the design of analogues of the fungicidal natural products crocacins A and D. Crowley PJ, Berry EA, Cromartie T, Daldal F, Godfrey CR, Lee DW, Phillips JE, Taylor A, Viner R. Bioorg Med Chem 16 10345-10355 (2008)
  158. A proposed common structure of substrates bound to mitochondrial processing peptidase. Kojima K, Kitada S, Ogishima T, Ito A. J Biol Chem 276 2115-2121 (2001)
  159. Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case. Aleshin AE, Gramatikova S, Hura GL, Bobkov A, Strongin AY, Stec B, Tainer JA, Liddington RC, Smith JW. Structure 17 1465-1475 (2009)
  160. Expression and one-step purification of a fully active polyhistidine-tagged cytochrome bc1 complex from Rhodobacter sphaeroides. Guergova-Kuras M, Salcedo-Hernandez R, Bechmann G, Kuras R, Gennis RB, Crofts AR. Protein Expr Purif 15 370-380 (1999)
  161. De novo metalloprotein design. Chalkley MJ, Mann SI, DeGrado WF. Nat Rev Chem 6 31-50 (2022)
  162. Large scale expression, purification and 2D crystallization of recombinant plant plasma membrane H+-ATPase. Jahn T, Dietrich J, Andersen B, Leidvik B, Otter C, Briving C, Kühlbrandt W, Palmgren MG. J Mol Biol 309 465-476 (2001)
  163. Hydrogen bonds between nitrogen donors and the semiquinone in the Qi-site of the bc1 complex. Dikanov SA, Holland JT, Endeward B, Kolling DR, Samoilova RI, Prisner TF, Crofts AR. J Biol Chem 282 25831-25841 (2007)
  164. Redox components of cytochrome bc-type enzymes in acidophilic prokaryotes. II. The Rieske protein of phylogenetically distant acidophilic organisms. Brugna M, Nitschke W, Asso M, Guigliarelli B, Lemesle-Meunier D, Schmidt C. J Biol Chem 274 16766-16772 (1999)
  165. Coupled plasmon-waveguide resonance spectroscopy studies of the cytochrome b6f/plastocyanin system in supported lipid bilayer membranes. Salamon Z, Huang D, Cramer WA, Tollin G. Biophys J 75 1874-1885 (1998)
  166. Cross-talk between mitochondrial malate dehydrogenase and the cytochrome bc1 complex. Wang Q, Yu L, Yu CA. J Biol Chem 285 10408-10414 (2010)
  167. Cytochrome c oxidase subunit III (COX3) gene, an informative marker for phylogenetic analysis and differentiation of Babesia species in China. Tian Z, Liu G, Yin H, Luo J, Guan G, Xie J, Luo J, Zheng J, Tian M, Yuan X, Wang F, Chen R, Wang H. Infect Genet Evol 18 13-17 (2013)
  168. Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites. Hayward JA, Rajendran E, Zwahlen SM, Faou P, van Dooren GG. PLoS Pathog 17 e1009211 (2021)
  169. Histidine placement in de novo-designed heme proteins. Gibney BR, Dutton PL. Protein Sci 8 1888-1898 (1999)
  170. Interaction of 2-n-heptyl-4-hydroxyquinoline-N-oxide with dimethyl sulfoxide reductase of Escherichia coli. Zhao Z, Weiner JH. J Biol Chem 273 20758-20763 (1998)
  171. Studies on inhibition of respiratory cytochrome bc1 complex by the fungicide pyrimorph suggest a novel inhibitory mechanism. Xiao YM, Esser L, Zhou F, Li C, Zhou YH, Yu CA, Qin ZH, Xia D. PLoS One 9 e93765 (2014)
  172. A transcriptome screen in yeast identifies a novel assembly factor for the mitochondrial complex III. Mathieu L, Marsy S, Saint-Georges Y, Jacq C, Dujardin G. Mitochondrion 11 391-396 (2011)
  173. Detection of heme oxygenase activity in a library of four-helix bundle proteins: towards the de novo synthesis of functional heme proteins. Monien BH, Drepper F, Sommerhalter M, Lubitz W, Haehnel W. J Mol Biol 371 739-753 (2007)
  174. Functional genetic screening reveals the role of mitochondrial cytochrome b as a mediator of FAS-induced apoptosis. Komarov AP, Rokhlin OW, Yu CA, Gudkov AV. Proc Natl Acad Sci U S A 105 14453-14458 (2008)
  175. Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells. Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J. Elife 10 e67624 (2021)
  176. Mass spectrometric characterization of mitochondrial electron transport complexes: subunits of the rat heart ubiquinol-cytochrome c reductase. Sun G, Kinter MT, Anderson VE. J Mass Spectrom 38 531-539 (2003)
  177. Mutations in the tether region of the iron-sulfur protein affect the activity and assembly of the cytochrome bc(1) complex of yeast mitochondria. Obungu VH, Wang Y, Amyot SM, Gocke CB, Beattie DS. Biochim Biophys Acta 1457 36-44 (2000)
  178. On the mechanism of quinol oxidation at the QP site in the cytochrome bc1 complex: studied using mutants lacking cytochrome bL or bH. Yang S, Ma HW, Yu L, Yu CA. J Biol Chem 283 28767-28776 (2008)
  179. Overexpression, purification, and crystallization of the membrane-bound fumarate reductase from Escherichia coli. Luna-Chavez C, Iverson TM, Rees DC, Cecchini G. Protein Expr Purif 19 188-196 (2000)
  180. Thermolysin and mitochondrial processing peptidase: how far structure-functional convergence goes. Makarova KS, Grishin NV. Protein Sci 8 2537-2540 (1999)
  181. X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery. Amporndanai K, Johnson RM, O'Neill PM, Fishwick CWG, Jamson AH, Rawson S, Muench SP, Hasnain SS, Antonyuk SV. IUCrJ 5 200-210 (2018)
  182. Characterization of two relacidines belonging to a novel class of circular lipopeptides that act against Gram-negative bacterial pathogens. Li Z, Chakraborty P, de Vries RH, Song C, Zhao X, Roelfes G, Scheffers DJ, Kuipers OP. Environ Microbiol 22 5125-5136 (2020)
  183. Effect of mutations in the cytochrome b ef loop on the electron-transfer reactions of the Rieske iron-sulfur protein in the cytochrome bc1 complex. Rajagukguk S, Yang S, Yu CA, Yu L, Durham B, Millett F. Biochemistry 46 1791-1798 (2007)
  184. Natural resistance to inhibitors of the ubiquinol cytochrome c oxidoreductase of Rubrivivax gelatinosus: sequence and functional analysis of the cytochrome bc(1) complex. Ouchane S, Agalidis I, Astier C. J Bacteriol 184 3815-3822 (2002)
  185. Phylogeny of Rieske/cytb complexes with a special focus on the Haloarchaeal enzymes. Baymann F, Schoepp-Cothenet B, Lebrun E, van Lis R, Nitschke W. Genome Biol Evol 4 720-729 (2012)
  186. Role of positively charged transmembrane segments in the insertion and assembly of mitochondrial inner-membrane proteins. Saint-Georges Y, Hamel P, Lemaire C, Dujardin G. Proc Natl Acad Sci U S A 98 13814-13819 (2001)
  187. Role of the -PEWY-glutamate in catalysis at the Q(o)-site of the Cyt bc(1) complex. Victoria D, Burton R, Crofts AR. Biochim Biophys Acta 1827 365-386 (2013)
  188. Studies on the topology of the protein import channel in relation to the plant mitochondrial processing peptidase integrated into the cytochrome bc1 complex. Dessi P, Rudhe C, Glaser E. Plant J 24 637-644 (2000)
  189. The N-terminus of the Qcr7 protein of the cytochrome bc(1) complex in S. cerevisiae may be involved in facilitating stability of the subcomplex with the Qcr8 protein and cytochrome b. Lee SY, Hunte C, Malaney S, Robinson BH. Arch Biochem Biophys 393 215-221 (2001)
  190. Universal free-energy landscape produces efficient and reversible electron bifurcation. Yuly JL, Zhang P, Lubner CE, Peters JW, Beratan DN. Proc Natl Acad Sci U S A 117 21045-21051 (2020)
  191. X-Ray absorption studies of Zn2+ binding sites in bacterial, avian, and bovine cytochrome bc1 complexes. Giachini L, Francia F, Veronesi G, Lee DW, Daldal F, Huang LS, Berry EA, Cocco T, Papa S, Boscherini F, Venturoli G. Biophys J 93 2934-2951 (2007)
  192. Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency. Marín-Buera L, García-Bartolomé A, Morán M, López-Bernardo E, Cadenas S, Hidalgo B, Sánchez R, Seneca S, Arenas J, Martín MA, Ugalde C. J Proteomics 113 38-56 (2015)
  193. Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III. Esser L, Zhou F, Zhou Y, Xiao Y, Tang WK, Yu CA, Qin Z, Xia D. J Biol Chem 291 25019-25031 (2016)
  194. Mitochondrial Disease-related Mutation G167P in Cytochrome b of Rhodobacter capsulatus Cytochrome bc1 (S151P in Human) Affects the Equilibrium Distribution of [2Fe-2S] Cluster and Generation of Superoxide. Borek A, Kuleta P, Ekiert R, Pietras R, Sarewicz M, Osyczka A. J Biol Chem 290 23781-23792 (2015)
  195. Plasmon waveguide resonance spectroscopic evidence for differential binding of oxidized and reduced Rhodobacter capsulatus cytochrome c2 to the cytochrome bc1 complex mediated by the conformation of the Rieske iron-sulfur protein. Devanathan S, Salamon Z, Tollin G, Fitch JC, Meyer TE, Berry EA, Cusanovich MA. Biochemistry 46 7138-7145 (2007)
  196. Reaction of Escherichia coli cytochrome bo(3) and mitochondrial cytochrome bc(1) with a photoreleasable decylubiquinol. Hansen KC, Schultz BE, Wang G, Chan SI. Biochim Biophys Acta 1456 121-137 (2000)
  197. Effects of electron transport inhibitors on iron reduction in Aeromonas hydrophila strain KB1. Woźnica A, Dzirba J, Mańka D, Łabuzek S. Anaerobe 9 125-130 (2003)
  198. Heterosubunit composition and crystal structures of a novel bacterial M16B metallopeptidase. Maruyama Y, Chuma A, Mikami B, Hashimoto W, Murata K. J Mol Biol 407 180-192 (2011)
  199. Kinetics of Electron Transfer within Cytochrome bc (1) and Between Cytochrome bc (1) and Cytochrome c. Millett F, Durham B. Photosynth Res 82 1-16 (2004)
  200. Molecular characterization of the membrane-bound quinol peroxidase functionally connected to the respiratory chain. Yamada H, Takashima E, Konishi K. FEBS J 274 853-866 (2007)
  201. Perfluoroalkylphosphocholines are poor protein-solubilizing surfactants, as tested with neutrophil plasma membranes. Der Mardirossian C, Krafft MP, Gulik-Krzywicki T, le Maire M, Lederer F. Biochimie 80 531-541 (1998)
  202. Stigmatellin induces reduction of iron-sulfur protein in the oxidized cytochrome bc1 complex. Gurung B, Yu L, Yu CA. J Biol Chem 283 28087-28094 (2008)
  203. Editorial The changing face of mitochondrial research. Capaldi RA. Trends Biochem Sci 25 212-214 (2000)
  204. The membrane-extrinsic domain of cytochrome b(558/566) from the archaeon Sulfolobus acidocaldarius performs pivoting movements with respect to the membrane surface. Schoepp-Cothenet B, Schütz M, Baymann F, Brugna M, Nitschke W, Myllykallio H, Schmidt C. FEBS Lett 487 372-376 (2001)
  205. A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, Kallijärvi J. Nat Commun 11 322 (2020)
  206. Adaptation of the Mitochondrial Genome in Cephalopods: Enhancing Proton Translocation Channels and the Subunit Interactions. Almeida D, Maldonado E, Vasconcelos V, Antunes A. PLoS One 10 e0135405 (2015)
  207. Crystal structure of bacterial cytochrome bc1 in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit. Esser L, Zhou F, Yu CA, Xia D. J Biol Chem 294 12007-12019 (2019)
  208. Dicyclohexylcarbodiimide inhibits proton pumping in ubiquinol:cytochrome c oxidoreductase of Rhodobacter sphaeroides and binds to aspartate-187 of cytochrome b. Wang Y, Obungu V, Beattie DS. Arch Biochem Biophys 352 193-198 (1998)
  209. Electron transfer and stability of the cytochrome b6f complex in a small domain deletion mutant of cytochrome f. Gong XS, Chung S, Fernández-Velasco JG. J Biol Chem 276 24365-24371 (2001)
  210. Exogenous administration of coenzyme Q10 restores mitochondrial oxygen consumption in the aged mouse brain. Takahashi K, Takahashi M. Mech Ageing Dev 134 580-586 (2013)
  211. Heliobacterial Rieske/cytb complex. Baymann F, Nitschke W. Photosynth Res 104 177-187 (2010)
  212. Models of the bis-histidine-coordinated ferricytochromes: Mössbauer and EPR spectroscopic studies of low-spin iron(III) tetrapyrroles of various electronic ground states and axial ligand orientations. Benda R, Schünemann V, Trautwein AX, Cai S, Reddy Polam J, Watson CT, Shokhireva TKh, Walker FA. J Biol Inorg Chem 8 787-801 (2003)
  213. Modification of inhibitor binding sites in the cytochrome bf complex by directed mutagenesis of cytochrome b(6) in Synechococcus sp. PCC 7002. Lee T, Metzger SU, Cho YS, Whitmarsh J, Kallas T. Biochim Biophys Acta 1504 235-247 (2001)
  214. Photo-induced cyclic electron transfer involving cytochrome bc1 complex and reaction center in the obligate aerobic phototroph Roseobacter denitrificans. Schwarze C, Carluccio AV, Venturoli G, Labahn A. Eur J Biochem 267 422-433 (2000)
  215. The 9 A projection structure of cytochrome b6f complex determined by electron crystallography. Bron P, Lacapère JJ, Breyton C, Mosser G. J Mol Biol 287 117-126 (1999)
  216. The Rieske Iron-Sulfur Protein: Import and Assembly into the Cytochrome bc(1) Complex of Yeast Mitochondria. Conte L, Zara V. Bioinorg Chem Appl 2011 363941 (2011)
  217. The involvement of serine 175 and alanine 185 of cytochrome b of Rhodobacter sphaeroides cytochrome bc1 complex in interaction with iron-sulfur protein. Tian H, Yu L, Mather MW, Yu CA. J Biol Chem 272 23722-23728 (1997)
  218. Antimycin A inhibits cytochrome b559-mediated cyclic electron flow within photosystem II. Takagi D, Ifuku K, Nishimura T, Miyake C. Photosynth Res 139 487-498 (2019)
  219. Domain swing upon His to Ala mutation in nitrite reductase of Pseudomonas aeruginosa. Brown K, Roig-Zamboni V, Cutruzzola' F, Arese M, Sun W, Brunori M, Cambillau C, Tegoni M. J Mol Biol 312 541-554 (2001)
  220. Hybrid fusions show that inter-monomer electron transfer robustly supports cytochrome bc1 function in vivo. Ekiert R, Czapla M, Sarewicz M, Osyczka A. Biochem Biophys Res Commun 451 270-275 (2014)
  221. Low-Temperature EPR Spectroscopy as a Probe-Free Technique for Monitoring Oxidants Formed in Tumor Cells and Tissues: Implications in Drug Resistance and OXPHOS-Targeted Therapies. Kalyanaraman B, Cheng G, Zielonka J, Bennett B. Cell Biochem Biophys 77 89-98 (2019)
  222. Models of the membrane-bound cytochromes: mössbauer spectra of crystalline low-spin ferriheme complexes having axial ligand plane dihedral angles ranging from 0 degree to 90 degrees. Teschner T, Yatsunyk L, Schünemann V, Paulsen H, Winkler H, Hu C, Scheidt WR, Walker FA, Trautwein AX. J Am Chem Soc 128 1379-1389 (2006)
  223. Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke. Zhang L, Lam WP, Lü L, Wang C, Wong YW, Lam LH, Tang HC, Wai MS, Wang M, Kwong WH, Ngai SM, Mak YT, Yew DT. Chin Med 5 35 (2010)
  224. Respiratory chain enzyme deficiency induces mitochondrial location of actin-binding gelsolin to modulate the oligomerization of VDAC complexes and cell survival. García-Bartolomé A, Peñas A, Marín-Buera L, Lobo-Jarne T, Pérez-Pérez R, Morán M, Arenas J, Martín MA, Ugalde C. Hum Mol Genet 26 2493-2506 (2017)
  225. Search for novel redox groups in mitochondrial NADH:ubiquinone oxidoreductase (complex I) by diode array UV/VIS spectroscopy. Schulte U, Abelmann A, Amling N, Brors B, Friedrich T, Kintscher L, Rasmussen T, Weiss H. Biofactors 8 177-186 (1998)
  226. Structure and reaction mechanisms of multifunctional mitochondrial cytochrome bc1 complex. Yu CA, Zhang L, Deng KP, Tian H, Xia D, Kim H, Deisenhofer J, Yu L. Biofactors 9 103-109 (1999)
  227. The cytochrome bc1 complex from Rhodovulum sulfidophilum is a dimer with six quinones per monomer and an additional 6-kDa component. Montoya G, te Kaat K, Rodgers S, Nitschke W, Sinning I. Eur J Biochem 259 709-718 (1999)
  228. The road to the crystal structure of the cytochrome bc1 complex from the anoxigenic, photosynthetic bacterium Rhodobacter sphaeroides. Xia D, Esser L, Elberry M, Zhou F, Yu L, Yu CA. J Bioenerg Biomembr 40 485-492 (2008)
  229. The semiquinone at the Qi site of the bc1 complex explored using HYSCORE spectroscopy and specific isotopic labeling of ubiquinone in Rhodobacter sphaeroides via (13)C methionine and construction of a methionine auxotroph. Hong S, de Almeida WB, Taguchi AT, Samoilova RI, Gennis RB, O'Malley PJ, Dikanov SA, Crofts AR. Biochemistry 53 6022-6031 (2014)
  230. pH-induced intramolecular electron transfer between the iron-sulfur protein and cytochrome c(1) in bovine cytochrome bc(1) complex. Zhang L, Tai CH, Yu L, Yu CA. J Biol Chem 275 7656-7661 (2000)
  231. Activities and conformational fitting of 1,4-naphthoquinone derivatives and other cyclic 1,4-diones tested in vitro against Pneumocystis carinii. Ball MD, Bartlett MS, Shaw M, Smith JW, Nasr M, Meshnick SR. Antimicrob Agents Chemother 45 1473-1479 (2001)
  232. Chapter 25 Analysis of electron transfer and superoxide generation in the cytochrome bc1 complex. Yu L, Yang S, Yin Y, Cen X, Zhou F, Xia D, Yu CA. Methods Enzymol 456 459-473 (2009)
  233. Cytochrome b6 arginine 214 of Synechococcus sp. PCC 7002, a key residue for quinone-reductase site function and turnover of the cytochrome bf complex. Nelson ME, Finazzi G, Wang QJ, Middleton-Zarka KA, Whitmarsh J, Kallas T. J Biol Chem 280 10395-10402 (2005)
  234. Domain movement of iron sulfur protein in cytochrome bc1 complex is facilitated by the electron transfer from cytochrome b(L) to b(H). Cen X, Yu L, Yu CA. FEBS Lett 582 523-526 (2008)
  235. Ilicicolin Inhibition and Binding at Center N of the Dimeric Cytochrome bc1 Complex Reveal Electron Transfer and Regulatory Interactions between Monomers. Covian R, Trumpower BL. J Biol Chem 284 8614-8620 (2009)
  236. Mitochondrial disease-related mutations at the cytochrome b-iron-sulfur protein (ISP) interface: Molecular effects on the large-scale motion of ISP and superoxide generation studied in Rhodobacter capsulatus cytochrome bc1. Ekiert R, Borek A, Kuleta P, Czernek J, Osyczka A. Biochim Biophys Acta 1857 1102-1110 (2016)
  237. Prebiological evolution and the metabolic origins of life. Pratt AJ. Artif Life 17 203-217 (2011)
  238. Letter Progress away from 'no crystals, no grant'. Preusch PC, Norvell JC, Cassatt JC, Cassman M. Nat Struct Biol 5 12-14 (1998)
  239. Purification and two-dimensional crystallization of highly active cytochrome b(6)f complex from spinach. Dietrich J, Kühlbrandt W. FEBS Lett 463 97-102 (1999)
  240. Rationalization of membrane protein crystallization with polyethylene glycol using a simple depletion model. Tanaka S, Ataka M, Onuma K, Kubota T. Biophys J 84 3299-3306 (2003)
  241. Role of the twin arginine protein transport pathway in the assembly of the Streptomyces coelicolor cytochrome bc1 complex. Hopkins A, Buchanan G, Palmer T. J Bacteriol 196 50-59 (2014)
  242. Selective cytotoxicity of epidithiodiketopiperazine DC1149B, produced by marine-derived Trichoderma lixii on the cancer cells adapted to glucose starvation. Tang R, Kimishima A, Ishida R, Setiawan A, Arai M. J Nat Med 74 153-158 (2020)
  243. Structure of the bc1 complex from Seculamonas ecuadoriensis, a jakobid flagellate with an ancestral mitochondrial genome. Marx S, Baumgärtner M, Kannan S, Braun HP, Lang BF, Burger G. Mol Biol Evol 20 145-153 (2003)
  244. A 3.3 Å-Resolution Structure of Hyperthermophilic Respiratory Complex III Reveals the Mechanism of Its Thermal Stability. Zhu G, Zeng H, Zhang S, Juli J, Pang X, Hoffmann J, Zhang Y, Morgner N, Zhu Y, Peng G, Michel H, Sun F. Angew Chem Int Ed Engl 59 343-351 (2020)
  245. Analysis of a Functional Dimer Model of Ubiquinol Cytochrome c Oxidoreductase. Bazil JN. Biophys J 113 1599-1612 (2017)
  246. Antimycin A-like molecules inhibit cyclic electron transport around photosystem I in ruptured chloroplasts. Taira Y, Okegawa Y, Sugimoto K, Abe M, Miyoshi H, Shikanai T. FEBS Open Bio 3 406-410 (2013)
  247. Assembly of the Rieske iron-sulphur protein into the cytochrome bf complex in thylakoid membranes of isolated pea chloroplasts. Kapazoglou A, Mould RM, Gray JC. Eur J Biochem 267 352-360 (2000)
  248. Binding of the respiratory chain inhibitor ametoctradin to the mitochondrial bc1 complex. Fehr M, Wolf A, Stammler G. Pest Manag Sci 72 591-602 (2016)
  249. Comparative sequence analysis of the Gdf6 locus reveals a duplicon-mediated chromosomal rearrangement in rodents and rapidly diverging coding and regulatory sequences. Mortlock DP, Portnoy ME, Chandler RL, NISC Comparative Sequencing Program, Green ED. Genomics 84 814-823 (2004)
  250. Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells. Lai B, Zhang L, Dong LY, Zhu YH, Sun FY, Zheng P. Neurobiol Dis 21 206-216 (2006)
  251. Intermonomer electron transfer between the b hemes of heterodimeric cytochrome bc(1). Lanciano P, Khalfaoui-Hassani B, Selamoglu N, Daldal F. Biochemistry 52 7196-7206 (2013)
  252. Molecular control of a bimodal distribution of quinone-analogue inhibitor binding sites in the cytochrome b(6)f complex. Yan J, Cramer WA. J Mol Biol 344 481-493 (2004)
  253. Non-inhibiting perturbation of the primary energy conversion site (Qo site) in Rhodobacter capsulatus ubihydroquinone: cytochrome c oxidoreductase (cytochrome bc1 complex). Sharp RE, Palmitessa A, Gibney BR, Moser CC, Daldal F, Dutton PL. FEBS Lett 431 423-426 (1998)
  254. Photosynthetic electron transfer through the cytochrome b6f complex can bypass cytochrome f. Fernández-Velasco JG, Jamshidi A, Gong XS, Zhou J, Ueng RY. J Biol Chem 276 30598-30607 (2001)
  255. Programmed cell death induced by (-)-8,9-dehydroneopeltolide in human promyelocytic leukemia HL-60 cells under energy stress conditions. Fuwa H, Sato M, Sasaki M. Mar Drugs 12 5576-5589 (2014)
  256. Comment Structural biology: dual approach to a light problem. Kühlbrandt W. Nature 426 399-400 (2003)
  257. The role of subunit VIII in the structural stability of the bc1 complex from Saccharomyces cerevisiae studied using hybrid complexes. Boumans H, Berden JA, Grivell LA. Eur J Biochem 249 762-769 (1997)
  258. Two unusual amino acid substitutions in cytochrome b of the colorless alga Polytomella spp.: correlation with the atypical spectral properties of the bH heme. Antaramian A, Funes S, Vázquez-acevedo M, Atteia A, Coria R, González-Halphen D. Arch Biochem Biophys 354 206-214 (1998)
  259. A robust genetic system for producing heterodimeric native and mutant cytochrome bc(1). Khalfaoui-Hassani B, Lanciano P, Daldal F. Biochemistry 52 7184-7195 (2013)
  260. An engineered cytochrome b6c1 complex with a split cytochrome b is able to support photosynthetic growth of Rhodobacter capsulatus. Saribas AS, Mandaci S, Daldal F. J Bacteriol 181 5365-5372 (1999)
  261. An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae. Glatigny A, Mathieu L, Herbert CJ, Dujardin G, Meunier B, Mucchielli-Giorgi MH. BMC Syst Biol 5 173 (2011)
  262. Electron transfer through arsenite oxidase: Insights into Rieske interaction with cytochrome c. Watson C, Niks D, Hille R, Vieira M, Schoepp-Cothenet B, Marques AT, Romão MJ, Santos-Silva T, Santini JM. Biochim Biophys Acta Bioenerg 1858 865-872 (2017)
  263. Failure to insert the iron-sulfur cluster into the Rieske iron-sulfur protein impairs both center N and center P of the cytochrome bc1 complex. Gutierrez-Cirlos EB, Merbitz-Zahradnik T, Trumpower BL. J Biol Chem 277 50703-50709 (2002)
  264. Formation of engineered intersubunit disulfide bond in cytochrome bc1 complex disrupts electron transfer activity in the complex. Ma HW, Yang S, Yu L, Yu CA. Biochim Biophys Acta 1777 317-326 (2008)
  265. Kinetic effects of the electrochemical proton gradient on plastoquinone reduction at the Qi site of the cytochrome b6f complex. Barbagallo RP, Breyton C, Finazzi G. J Biol Chem 275 26121-26127 (2000)
  266. Modelling of BCS1L-related human mitochondrial disease in Drosophila melanogaster. Brischigliaro M, Frigo E, Corrà S, De Pittà C, Szabò I, Zeviani M, Costa R. J Mol Med (Berl) 99 1471-1485 (2021)
  267. Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II. Yamamoto K, Tashiro E, Motohashi K, Seto H, Imoto M. J Antibiot (Tokyo) 65 211-214 (2012)
  268. Photoinitiated electron transfer within the Paracoccus denitrificans cytochrome bc1 complex: mobility of the iron-sulfur protein is modulated by the occupant of the Q(o) site. Havens J, Castellani M, Kleinschroth T, Ludwig B, Durham B, Millett F. Biochemistry 50 10462-10472 (2011)
  269. Preliminary molecular characterization and crystallization of mitochondrial respiratory complex II from porcine heart. Huo X, Su D, Wang A, Zhai Y, Xu J, Li X, Bartlam M, Sun F, Rao Z. FEBS J 274 1524-1529 (2007)
  270. Role of domain swapping in the hetero-oligomeric cytochrome b6f lipoprotein complex. Agarwal R, Hasan SS, Jones LM, Stofleth JT, Ryan CM, Whitelegge JP, Kehoe DM, Cramer WA. Biochemistry 54 3151-3163 (2015)
  271. Structural insights into the electron/proton transfer pathways in the quinol:fumarate reductase from Desulfovibrio gigas. Guan HH, Hsieh YC, Lin PJ, Huang YC, Yoshimura M, Chen LY, Chen SK, Chuankhayan P, Lin CC, Chen NC, Nakagawa A, Chan SI, Chen CJ. Sci Rep 8 14935 (2018)
  272. The metabolic inhibitor antimycin A can disrupt cell-to-cell communication by an ATP- and Ca(2+)-independent mechanism. Plaisance I, Duthe F, Sarrouilhe D, Hervé JC. Pflugers Arch 447 181-194 (2003)
  273. Two distinct states of the thylakoid bf complex. Heimann S, Klughammer C, Schreiber U. FEBS Lett 426 126-130 (1998)
  274. Binding of imidazole to the heme of cytochrome c1 and inhibition of the bc1 complex from Rhodobacter sphaeroides: II. Kinetics and mechanism of binding. Kokhan O, Shinkarev VP, Wraight CA. J Biol Chem 285 22522-22531 (2010)
  275. Determination of the binding rate constants of stigmatellin and UHDBT to bovine cytochrome bc(1) complex by cytochrome c(1) oxidation. Zhang L, Snyder C, Trumpower BL, Yu L, Yu CA. FEBS Lett 460 349-352 (1999)
  276. Dimer crystallization of chiral proteoids. Wang PY, Mason TG. Phys Chem Chem Phys 19 7167-7175 (2017)
  277. Effect of motional restriction on the unfolding properties of a cytochrome c featuring a His/Met-His/His ligation switch. Ranieri A, Bortolotti CA, Battistuzzi G, Borsari M, Paltrinieri L, Di Rocco G, Sola M. Metallomics 6 874-884 (2014)
  278. Emergence of cytochrome bc complexes in the context of photosynthesis. Dibrova DV, Shalaeva DN, Galperin MY, Mulkidjanian AY. Physiol Plant 161 150-170 (2017)
  279. Functional complementation analysis of yeast bc1 mutants. A study of the mitochondrial import of heterologous and hybrid proteins. van Wilpe S, Boumans H, Lobo-Hajdu G, Grivell LA, Berden JA. Eur J Biochem 264 825-832 (1999)
  280. Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene. Pember SO, Fleck LC, Moberg WK, Walker MP. Arch Biochem Biophys 435 280-290 (2005)
  281. Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets, and Associated Mechanisms of Resistance. Bown L, Srivastava SK, Piercey BM, McIsaac CK, Tahlan K. J Membr Biol 251 105-117 (2018)
  282. The thankless task of playing genetics with mammalian mitochondrial DNA: a 30-year review. Bayona-Bafaluy MP, Fernández-Silva P, Enríquez JA. Mitochondrion 2 3-25 (2002)
  283. Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1. Pacheco R, Quezada SA, Kalergis AM, Becker MI, Ferreira J, De Ioannes AE. Biol Res 54 35 (2021)
  284. Aromatic amino acids in the Rieske iron-sulfur protein do not form an obligatory conduit for electron transfer from the iron-sulfur cluster to the heme of cytochrome c1 in the cytochrome bc1 complex. Snyder CH, Denke E, Trumpower BL. Biochim Biophys Acta 1410 237-247 (1999)
  285. Chapter 5 Use of ruthenium photooxidation techniques to study electron transfer in the cytochrome bc1 complex. Millett F, Durham B. Methods Enzymol 456 95-109 (2009)
  286. Characterization and submitochondrial localization of the alpha subunit of the mitochondrial processing peptidase from the aquatic fungus Blastocladiella emersonii. Rocha CR, Gomes SL. J Bacteriol 181 4257-4265 (1999)
  287. Characterization of mutations in crucial residues around the Q(o) binding site of the cytochrome bc complex from Paracoccus denitrificans. Kleinschroth T, Anderka O, Ritter M, Stocker A, Link TA, Ludwig B, Hellwig P. FEBS J 275 4773-4785 (2008)
  288. DRUIDS--detection of regions with unexpected internal deviation from stationarity. Fedrigo O, Adams DC, Naylor GJ. J Exp Zool B Mol Dev Evol 304 119-128 (2005)
  289. Effects of electron transfer on the stability of hydrogen bonds. Porter TM, Heim GP, Kubiak CP. Chem Sci 8 7324-7329 (2017)
  290. Exploring the Molecular Basis of Qo bc1 Complex Inhibitors Activity to Find Novel Antimalarials Hits. Carrasco MP, Gut J, Rodrigues T, Ribeiro MH, Lopes F, Rosenthal PJ, Moreira R, Dos Santos DJ. Mol Inform 32 659-670 (2013)
  291. Localization of acidic residues involved in the proton pumping activity of the bovine heart mitochondrial bc1 complex. Cocco T, Di Paola M, Papa S, Lorusso M. FEBS Lett 456 37-40 (1999)
  292. Membrane protein structures: the known world expands. Garavito RM. Curr Opin Biotechnol 9 344-349 (1998)
  293. Mitochondrial Targeting in an Anti-Austerity Approach Involving Bioactive Metabolites Isolated from the Marine-Derived Fungus Aspergillus sp. Abdel-Naime WA, Kimishima A, Setiawan A, Fahim JR, Fouad MA, Kamel MS, Arai M. Mar Drugs 18 E555 (2020)
  294. Molecular basis for the enantioselective binding of a novel class of cytochrome bc1 complex inhibitors. Zheng YJ. J Mol Graph Model 25 71-76 (2006)
  295. Q-Band resonance Raman investigation of turnip cytochrome f and Rhodobacter capsulatus cytochrome c1. Gao F, Qin H, Knaff DB, Zhang L, Yu L, Yu CA, Gray KA, Daldal F, Ondrias MR. Biochim Biophys Acta 1430 203-213 (1999)
  296. Reperfusion mediates heme impairment with increased protein cysteine sulfonation of mitochondrial complex III in the post-ischemic heart. Chen CL, Kang PT, Zhang L, Xiao K, Zweier JL, Chilian WM, Chen YR. J Mol Cell Cardiol 161 23-38 (2021)
  297. Role of Arg-166 in yeast cytochrome C1. Ahmad Z, Sherman F. J Biol Chem 276 18450-18456 (2001)
  298. Synthesis, characterization and cation-induced dimerization of new aza-crown ether-appended metalloporphyrins. Mikhalitsyna EA, Tyurin VS, Zamylatskov IA, Khrustalev VN, Beletskaya IP. Dalton Trans 41 7624-7636 (2012)
  299. The acidic domain of cytochrome c₁ in paracoccus denitrificans, analogous to the acidic subunits in eukaryotic bc₁ complexes, is not involved in the electron transfer reaction to its native substrate cytochrome c(552). Castellani M, Havens J, Kleinschroth T, Millett F, Durham B, Malatesta F, Ludwig B. Biochim Biophys Acta 1807 1383-1389 (2011)
  300. The cytochrome b Zn binding amino acid residue histidine 291 is essential for ubihydroquinone oxidation at the Qo site of bacterial cytochrome bc1. Francia F, Malferrari M, Lanciano P, Steimle S, Daldal F, Venturoli G. Biochim Biophys Acta 1857 1796-1806 (2016)
  301. A compensatory double mutation of the alanine-86 to leucine mutant located in the hinge region of the iron-sulfur protein of the yeast cytochrome bc1 complex. Ebert CE, Beattie DS. Arch Biochem Biophys 429 16-22 (2004)
  302. Analysis of the role of detergent mixtures on the crystallization of the reaction center of Photosystem II. Rukhman V, Lerner N, Adir N. Photosynth Res 65 249-259 (2000)
  303. Cloning and sequence analysis of the structural gene for the bc1-type Rieske iron-sulfur protein from Thermus thermophilus HB8. Gatti DL, Tarr G, Fee JA, Ackerman SH. J Bioenerg Biomembr 30 223-233 (1998)
  304. DCCD inhibits the reactions of the iron-sulfur protein in Rhodobacter sphaeroides chromatophores. Shinkarev VP, Ugulava NB, Crofts AR, Wraight CA. Biochemistry 39 16206-16212 (2000)
  305. Deletion of the 6-kDa subunit affects the activity and yield of the bc1 complex from Rhodovulum sulfidophilum. Rodgers S, Moser C, Martinez-Julvez M, Sinning I. Eur J Biochem 267 3753-3761 (2000)
  306. Different protonation equilibria of 4-methylimidazole and acetic acid. Gu W, Helms V. Chemphyschem 8 2445-2451 (2007)
  307. Effect of mutations of arginine 94 on proton pumping, electron transfer, and superoxide anion generation in cytochrome b of the bc1 complex from Rhodobacter sphaeroides. Qu YG, Zhou F, Yu L, Yu CA. J Biol Chem 288 1047-1054 (2013)
  308. Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides. Binding mode of vitamin K derivatives. Hucke O, Schmid R, Labahn A. Eur J Biochem 269 1096-1108 (2002)
  309. Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together. Vanoni MA. Open Biol 11 210010 (2021)
  310. Isolated transmembrane helices arranged across a membrane: computational studies. Tseitin VM, Nikiforovich GV. Protein Eng 12 305-311 (1999)
  311. Membrane potential genesis in Nitella cells, mitochondria, and thylakoids. Kitasato H. J Plant Res 116 401-418 (2003)
  312. Molecular modeling studies of the DCCD-treated cytochrome bc1 complex: predicted conformational changes and inhibition of proton translocation. Wang Y, Beattie DS. J Bioenerg Biomembr 34 81-88 (2002)
  313. Proteome changes induced by Pyrenophora tritici-repentis ToxA in both insensitive and sensitive wheat indicate senescence-like signaling. Day J, Gietz RD, Rampitsch C. Proteome Sci 13 3 (2015)
  314. Structural and functional contributions of lipids to the stability and activity of the photosynthetic cytochrome b6f lipoprotein complex. Bhaduri S, Zhang H, Erramilli S, Cramer WA. J Biol Chem 294 17758-17767 (2019)
  315. Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials. Amporndanai K, Pinthong N, O'Neill PM, Hong WD, Amewu RK, Pidathala C, Berry NG, Leung SC, Ward SA, Biagini GA, Hasnain SS, Antonyuk SV. Biology (Basel) 11 1109 (2022)
  316. The functional role of conserved acidic residues of the Qcr7 protein of the cytochrome bc(1) complex in Saccharomyces cerevisiae. Lee SY, Raha S, Nagar B, Robinson BH. Arch Biochem Biophys 393 207-214 (2001)
  317. Why is it so difficult to construct Q(i) site mutants in Chlamydomonas reinhardtii? de Lacroix de Lavalette A, Barbagallo RP, Zito F. C R Biol 331 510-517 (2008)
  318. An atypical cytochrome b in the colorless alga Polytomella spp.: the high potential bH heme exhibits a double transition in the alpha-peak of its absorption spectrum. Gutiérrez-Cirlos EB, Gómez-Lojero C, Vázquez-Acevedo M, Pérez-Martínez X, González-Halphen D. Arch Biochem Biophys 353 322-330 (1998)
  319. Determining the topology of an integral membrane protein. Green N, Fang H, Kalies KU, Canfield V. Curr Protoc Cell Biol Chapter 5 Unit 5.2 (2001)
  320. Editing of the grapevine mitochondrial cytochrome b mRNA and molecular modeling of the protein. Islas-Osuna MA, Silva-Moreno B, Caceres-Carrizosa N, García-Robles JM, Sotelo-Mundo RR, Yepiz-Plascencia GM. Biochimie 88 431-435 (2006)
  321. Electron tunneling in proteins program. Hagras MA, Stuchebrukhov AA. J Comput Chem 37 1388-1395 (2016)
  322. First complete mitochondrial genome of the South American annual fish Austrolebias charrua (Cyprinodontiformes: Rivulidae): peculiar features among cyprinodontiforms mitogenomes. Gutiérrez V, Rego N, Naya H, García G. BMC Genomics 16 879 (2015)
  323. Editorial Looking Back to the Future of Mitochondrial Research. Bernardi P. Front Physiol 12 682467 (2021)
  324. Structural snapshots of the cellular folded protein translocation machinery Bcs1. Xia D. FEBS J 288 2870-2883 (2021)
  325. The High-Spin Heme b L Mutant Exposes Dominant Reaction Leading to the Formation of the Semiquinone Spin-Coupled to the [2Fe-2S]+ Cluster at the Qo Site of Rhodobacter capsulatus Cytochrome bc 1. Sarewicz M, Pintscher S, Bujnowicz Ł, Wolska M, Artur Osyczka. Front Chem 9 658877 (2021)
  326. The alpha 1-helix in the extra-membranous domain contributes to the stability of the iron-sulfur protein of the cytochrome bc1 complex. Obungu VH, Beattie DS. Arch Biochem Biophys 359 128-132 (1998)
  327. [Glycation of mitochondrial proteins, oxidative stress and aging]. Naudí A, Jové M, Ayala V, Portero-Otín M, Pamplona R. Rev Esp Geriatr Gerontol 45 156-166 (2010)
  328. A concerted ATPase cycle of the protein transporter AAA-ATPase Bcs1. Pan Y, Zhan J, Jiang Y, Xia D, Scheuring S. Nat Commun 14 6369 (2023)
  329. Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III2 by cryo-EM. Wieferig JP, Kühlbrandt W. IUCrJ 10 27-37 (2023)
  330. Crystallization of proteins from soluble cytochrome P-450cam to membrane protein cytochrome bc(1) complex. Yu CA, Yu L. Biochem Biophys Res Commun 312 191-195 (2003)
  331. Exogenous ubiquinol analogues affect the fluorescence of NCD-4 bound to aspartate-160 of yeast cytochrome b. Wang Y, Bruel C, Yan L, Beattie DS. J Bioenerg Biomembr 30 455-464 (1998)
  332. Heteroplasmic Mutations and Polymorphisms in the Cyb Gene of Mitochondrial DNA in Canine Mast Cell Tumours. Śmiech A, Ślaska B, Bownik A, Grzybowska-Szatkowska L, Dudka J, Łopuszyński W. In Vivo 33 57-63 (2019)
  333. How Does Mitochondrial Protein-Coding Gene Expression in Fejervarya kawamurai (Anura: Dicroglossidae) Respond to Extreme Temperatures? Wang JY, Zhang LH, Hong YH, Cai LN, Storey KB, Zhang JY, Zhang SS, Yu DN. Animals (Basel) 13 3015 (2023)
  334. Identification of hydrogen bonding network for proton transfer at the quinol oxidation site of Rhodobacter capsulatus cytochrome bc1. Borek A, Wójcik-Augustyn A, Kuleta P, Ekiert R, Osyczka A. J Biol Chem 299 105249 (2023)
  335. In Silico Modeling of the Mitochondrial Pumping Complexes with Markov State Models. Springett R. Methods Mol Biol 2276 425-439 (2021)
  336. New methods for determining proton pumping ability and electron transfer activity of the cytochrome bc1 complex. Qu Y, Dong F. Acta Biochim Biophys Sin (Shanghai) 47 114-120 (2015)
  337. Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III-specific assembly factor in mitochondria. Chojnacka KJ, Elancheliyan P, Mussulini BHM, Mohanraj K, Callegari S, Gosk A, Banach T, Góral T, Szczepanowska K, Rehling P, Serwa RA, Chacinska A. Mol Biol Cell 33 ar29 (2022)
  338. Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc1 complexes. Esser L, Zhou F, Zeher A, Wu W, Huang R, Yu CA, Lane KD, Wellems TE, Xia D. J Biol Chem 299 104860 (2023)
  339. Synthesis of potent antifungal 3,4-dichloroisothiazole-based strobilurins with both direct fungicidal activity and systemic acquired resistance. Yang D, Qi X, Zhou X, Li Z, Zhou H, Fan Z. RSC Med Chem 13 429-435 (2022)
  340. Tyrosine triad at the interface between the Rieske iron-sulfur protein, cytochrome c1 and cytochrome c2 in the bc1 complex of Rhodobacter capsulatus. Kyndt JA, Fitch JC, Berry RE, Stewart MC, Whitley K, Meyer TE, Walker FA, Cusanovich MA. Biochim Biophys Acta 1817 811-818 (2012)


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