PDBe 1qab

X-ray diffraction
3.2Å resolution

The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transthyretin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 127 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
  • Canonical: P02766 (Residues: 21-147; Coverage: 100%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain
Retinol-binding protein 4 Chains: E, F
Molecule details ›
Chains: E, F
Length: 180 amino acids
Theoretical weight: 20.44 KDa
Source organism: Homo sapiens
  • Canonical: P02753 (Residues: 22-201; Coverage: 98%)
Gene names: PRO2222, RBP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P41212
Unit cell:
a: 140.23Å b: 140.23Å c: 124.08Å
α: 90° β: 90° γ: 90°
R R work R free
0.278 0.278 0.403