PDBe 1qa9

X-ray diffraction
3.2Å resolution

Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T-cell surface antigen CD2 Chains: A, C
Molecule details ›
Chains: A, C
Length: 102 amino acids
Theoretical weight: 12.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P06729 (Residues: 28-129; Coverage: 31%)
Gene names: CD2, SRBC
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Lymphocyte function-associated antigen 3 Chains: B, D
Molecule details ›
Chains: B, D
Length: 95 amino acids
Theoretical weight: 11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19256 (Residues: 30-123; Coverage: 42%)
Gene names: CD58, LFA3
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: C2
Unit cell:
a: 179.82Å b: 33.47Å c: 108.43Å
α: 90° β: 121.76° γ: 90°
R-values:
R R work R free
0.223 0.223 0.281
Expression system: Escherichia coli