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Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 3.1.3.48: Protein-tyrosine-phosphatase

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Systematic name:
Protein-tyrosine-phosphate phosphohydrolase
Alternative Name(s):
  • (Phosphotyrosine)protein phosphatase
  • PPT-phosphatase
  • PTP-phosphatase
  • PTPase
  • Phosphoprotein phosphatase (phosphotyrosine)
  • Phosphotyrosine histone phosphatase
  • Phosphotyrosine phosphatase
  • Phosphotyrosine protein phosphatase
  • Phosphotyrosylprotein phosphatase
  • Protein phosphotyrosine phosphatase
  • Tyrosine O-phosphate phosphatase
  • Tyrosylprotein phosphatase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00595
Domain description: PDZ domain
Occurring in:
  1. Tyrosine-protein phosphatase non-receptor type 13
The deposited structure of PDB entry 1q7x contains 1 copy of Pfam domain PF00595 (PDZ domain) in Tyrosine-protein phosphatase non-receptor type 13. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001478
Domain description: PDZ domain
Occurring in:
  1. Tyrosine-protein phosphatase non-receptor type 13
IPR036034
Domain description: PDZ superfamily
Occurring in:
  1. Tyrosine-protein phosphatase non-receptor type 13

Structure domain

CATH CATH domain
2.30.42.10
Class: Mainly Beta
Architecture: Roll
Topology: Pdz3 Domain
Homology: Pdz3 Domain
Occurring in:
  1. Tyrosine-protein phosphatase non-receptor type 13
The deposited structure of PDB entry 1q7x contains 1 copy of CATH domain 2.30.42.10 (Pdz3 Domain) in Tyrosine-protein phosphatase non-receptor type 13. Showing 1 copy in chain A.
SCOP SCOP annotation
50157
Class: All beta proteins
Fold: PDZ domain-like
Superfamily: PDZ domain-like
Occurring in:
  1. Tyrosine-protein phosphatase non-receptor type 13
The deposited structure of PDB entry 1q7x contains 1 copy of SCOP domain 50157 (PDZ domain) in Tyrosine-protein phosphatase non-receptor type 13. Showing 1 copy in chain A.

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