X-ray diffraction
1.9Å resolution

Rv1170 (MshB) from Mycobacterium tuberculosis


Function and Biology Details

Reaction catalysed:
1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H(2)O = 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + acetate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 328 amino acids
Theoretical weight: 34.88 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
  • Canonical: P9WJN3 (Residues: 1-303; Coverage: 100%)
Gene names: Rv1170, mshB
Sequence domains: GlcNAc-PI de-N-acetylase
Structure domains: LmbE-like

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 71.69Å b: 83.74Å c: 95.65Å
α: 90° β: 90° γ: 90°
R R work R free
0.19 0.19 0.215
Expression system: Escherichia coli