1q6i

X-ray diffraction
2.25Å resolution

Crystal structure of a truncated form of FkpA from Escherichia coli, in complex with immunosuppressant FK506

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 24.29 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P45523 (Residues: 26-249; Coverage: 91%)
Gene names: JW3309, b3347, fkpA, yzzS
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 37.14Å b: 85.44Å c: 159.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.253
Expression system: Escherichia coli