› 1q55

Electron Microscopy
30Å resolution

W-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography

Released:
DOI: 10.2210/pdb1q55/pdb
PDB entry 1q55 coloured by chain, front view.
PDB entry 1q55 coloured by chain, side view.
PDB entry 1q55 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Untangling desmosomal knots with electron tomography.
He W, Cowin P, Stokes DL
Science 302 109-13 (2003)
PMID: 14526082
Related structures: EMD-1052

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162402 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
EP-cadherin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 880 amino acids
Theoretical weight: 97.75 KDa
Source organism: Mus musculus

Ligands and Environments

3 bound ligands:
Ligand NAG 52 x NAG
Ligand NDG 8 x NDG
Ligand CA 48 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 30Å
Relevant EMDB volumes: EMD-1052

Quick links

Citations

57 review citations

Regulation of cadherin-mediated adhesion in morphogenesis.
Gumbiner BM. (2005)
56 more

6 mentions without citation

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes.
Szpirer C. (2020)
5 more