Function and Biology Details
Reactions catalysed:
Phenylpyruvate = phenylacetaldehyde + CO(2)
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO(2)
(3S)-3-methyl-2-oxopentanoate = 2-methylbutanal + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Thiamine pyrophosphate (TPP)-dependent enzyme
- Thiamin diphosphate-binding fold
- Thiamine pyrophosphate enzyme, central domain
- Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
- TPP-binding enzyme, conserved site
- Thiamine pyrophosphate enzyme, C-terminal TPP-binding
- DHS-like NAD/FAD-binding domain superfamily
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate decarboxylase isozyme 1
Molecule details ›
Chains: A, B
Length: 556 amino acids
Theoretical weight: 60.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
Sequence domains:
Length: 556 amino acids
Theoretical weight: 60.87 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
- Canonical:
P06169 (Residues: 1-556; Coverage: 99%)
Sequence domains:
- Thiamine pyrophosphate enzyme, central domain
- Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
