1px5

X-ray diffraction
1.74Å resolution

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2'-5'-oligoadenylate synthase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 349 amino acids
Theoretical weight: 40.42 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q29599 (Residues: 1-349; Coverage: null%)
Gene name: OAS1
Structure domains:

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P21
Unit cell:
a: 46.524Å b: 132.601Å c: 57.305Å
α: 90° β: 99.19° γ: 90°
R-values:
R R work R free
0.187 0.187 0.224
Expression system: Escherichia coli BL21(DE3)