Function and Biology

Domain-wise fitting of the crystal structure of T.thermophilus EF-G into the low resolution map of the release complex.Puromycin.EFG.GDPNP of E.coli 70S ribosome.

Source organism: Thermus thermophilus
Biochemical function: ribosome binding
Biological process: ribosome disassembly
Cellular component: cytosol

Sequence families

Pfam Protein families (Pfam)
PF00679
Domain description: Elongation factor G C-terminus
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of Pfam domain PF00679 (Elongation factor G C-terminus) in Elongation factor G. Showing 1 copy in chain A.

PF03764
Domain description: Elongation factor G, domain IV
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of Pfam domain PF03764 (Elongation factor G, domain IV) in Elongation factor G. Showing 1 copy in chain A.

PF14492
Domain description: Elongation Factor G, domain III
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of Pfam domain PF14492 (Elongation Factor G, domain III) in Elongation factor G. Showing 1 copy in chain A.

PF03144
Domain description: Elongation factor Tu domain 2
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of Pfam domain PF03144 (Elongation factor Tu domain 2) in Elongation factor G. Showing 1 copy in chain A.

PF00009
Domain description: Elongation factor Tu GTP binding domain
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of Pfam domain PF00009 (Elongation factor Tu GTP binding domain) in Elongation factor G. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000795
Domain description: Translational (tr)-type GTP-binding domain
Occurring in:
  1. Elongation factor G
IPR000640
Domain description: Elongation factor EFG, domain V-like
Occurring in:
  1. Elongation factor G
IPR005517
Domain description: Translation elongation factor EFG/EF2, domain IV
Occurring in:
  1. Elongation factor G
IPR035647
Domain description: EF-G domain III/V-like
Occurring in:
  1. Elongation factor G
IPR004540
Domain description: Translation elongation factor EFG/EF2
Occurring in:
  1. Elongation factor G
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Elongation factor G
IPR035649
Domain description: EFG, domain V
Occurring in:
  1. Elongation factor G
IPR014721
Domain description: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
  1. Elongation factor G
IPR047872
Domain description: Elongation factor G, domain IV
Occurring in:
  1. Elongation factor G
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. Elongation factor G
IPR009022
Domain description: Elongation factor G, domain III
Occurring in:
  1. Elongation factor G
IPR041095
Domain description: Elongation Factor G, domain II
Occurring in:
  1. Elongation factor G
IPR004161
Domain description: Translation elongation factor EFTu-like, domain 2
Occurring in:
  1. Elongation factor G
IPR009000
Domain description: Translation protein, beta-barrel domain superfamily
Occurring in:
  1. Elongation factor G
IPR031157
Domain description: Tr-type G domain, conserved site
Occurring in:
  1. Elongation factor G
IPR005225
Domain description: Small GTP-binding protein domain
Occurring in:
  1. Elongation factor G

Structure domain

SCOP SCOP annotation
58120
Class: Low resolution protein structures
Fold: Ribosome and ribosomal fragments
Superfamily: Ribosome and ribosomal fragments
Occurring in:
  1. Elongation factor G
The deposited structure of PDB entry 1pn6 contains 1 copy of SCOP domain 58120 (Ribosome complexes) in Elongation factor G. Showing 1 copy in chain A.