X-ray diffraction
1.75Å resolution

Acetyl CoA Synthetase, Salmonella enterica


Function and Biology Details

Reaction catalysed:
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Acetyl-coenzyme A synthetase Chains: A, B
Molecule details ›
Chains: A, B
Length: 652 amino acids
Theoretical weight: 72.18 KDa
Source organism: Salmonella enterica
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q8ZKF6 (Residues: 1-652; Coverage: 100%)
Gene names: STM4275, acs
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand COA 2 x COA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P21
Unit cell:
a: 59.994Å b: 143.016Å c: 71.731Å
α: 90° β: 91.32° γ: 90°
R R work R free
0.184 0.184 0.211
Expression system: Escherichia coli BL21(DE3)