Articles - 1pg0 mentioned but not cited (3)
- Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate. Larson ET, Kim JE, Zucker FH, Kelley A, Mueller N, Napuli AJ, Verlinde CL, Fan E, Buckner FS, Van Voorhis WC, Merritt EA, Hol WG. Biochimie 93 570-582 (2011)
- Adaptive landscape flattening allows the design of both enzyme: Substrate binding and catalytic power. Opuu V, Nigro G, Nigro G, Gaillard T, Schmitt E, Mechulam Y, Simonson T. PLoS Comput Biol 16 e1007600 (2020)
- Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation. Elbaramawi SS, Eissa AG, Noureldin NA, Simons C. Pharmaceuticals (Basel) 16 1263 (2023)
Reviews citing this publication (4)
- Geometry of nonbonded interactions involving planar groups in proteins. Chakrabarti P, Bhattacharyya R. Prog Biophys Mol Biol 95 83-137 (2007)
- Emergence and evolution. Bullwinkle TJ, Ibba M. Top Curr Chem 344 43-87 (2014)
- Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors. Lux MC, Standke LC, Tan DS. J Antibiot (Tokyo) 72 325-349 (2019)
- Non-canonical Amino Acid Substrates of E. coli Aminoacyl-tRNA Synthetases. Hartman MCT. Chembiochem 23 e202100299 (2022)
Articles citing this publication (36)
- A study of communication pathways in methionyl- tRNA synthetase by molecular dynamics simulations and structure network analysis. Ghosh A, Vishveshwara S. Proc Natl Acad Sci U S A 104 15711-15716 (2007)
- Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Link AJ, Vink MKS, Agard NJ, Prescher JA, Bertozzi CR, Tirrell DA. Proc Natl Acad Sci U S A 103 10180-10185 (2006)
- Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase. Palencia A, Crépin T, Vu MT, Lincecum TL, Martinis SA, Cusack S. Nat Struct Mol Biol 19 677-684 (2012)
- Achieving error-free translation; the mechanism of proofreading of threonyl-tRNA synthetase at atomic resolution. Dock-Bregeon AC, Rees B, Torres-Larios A, Bey G, Caillet J, Moras D. Mol Cell 16 375-386 (2004)
- Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo. Tanrikulu IC, Schmitt E, Mechulam Y, Goddard WA, Tirrell DA. Proc Natl Acad Sci U S A 106 15285-15290 (2009)
- Fluorine-protein interactions and ¹⁹F NMR isotropic chemical shifts: An empirical correlation with implications for drug design. Dalvit C, Vulpetti A. ChemMedChem 6 104-114 (2011)
- Allosteric communication in cysteinyl tRNA synthetase: a network of direct and indirect readout. Ghosh A, Sakaguchi R, Liu C, Vishveshwara S, Hou YM. J Biol Chem 286 37721-37731 (2011)
- Inhibition of methionyl-tRNA synthetase by REP8839 and effects of resistance mutations on enzyme activity. Green LS, Bullard JM, Ribble W, Dean F, Ayers DF, Ochsner UA, Janjic N, Jarvis TC. Antimicrob Agents Chemother 53 86-94 (2009)
- Organic fluorine as a polypeptide building element: in vivo expression of fluorinated peptides, proteins and proteomes. Merkel L, Budisa N. Org Biomol Chem 10 7241-7261 (2012)
- Prospects of In vivo Incorporation of Non-canonical Amino Acids for the Chemical Diversification of Antimicrobial Peptides. Baumann T, Nickling JH, Bartholomae M, Buivydas A, Kuipers OP, Budisa N. Front Microbiol 8 124 (2017)
- Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes. Powers R, Mirkovic N, Goldsmith-Fischman S, Acton TB, Chiang Y, Huang YJ, Ma L, Rajan PK, Cort JR, Kennedy MA, Liu J, Rost B, Honig B, Murray D, Montelione GT. Protein Sci 14 2849-2861 (2005)
- Using molecular dynamics to map interaction networks in an aminoacyl-tRNA synthetase. Budiman ME, Knaggs MH, Fetrow JS, Alexander RW. Proteins 68 670-689 (2007)
- Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance. Cheung J, Mahmood A, Kalathur R, Liu L, Carlier PR. Structure 26 130-136.e2 (2018)
- Screening of quinoline, 1,3-benzoxazine, and 1,3-oxazine-based small molecules against isolated methionyl-tRNA synthetase and A549 and HCT116 cancer cells including an in silico binding mode analysis. Bharathkumar H, Mohan CD, Rangappa S, Kang T, Keerthy HK, Fuchs JE, Kwon NH, Bender A, Kim S, Basappa, Rangappa KS. Org Biomol Chem 13 9381-9387 (2015)
- The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway. Tremblay LW, Fan F, Vetting MW, Blanchard JS. Biochemistry 47 13326-13335 (2008)
- High-throughput screening for methionyl-tRNA synthetases that enable residue-specific incorporation of noncanonical amino acids into recombinant proteins in bacterial cells. Yoo TH, Tirrell DA. Angew Chem Int Ed Engl 46 5340-5343 (2007)
- A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site. Yanagisawa T, Sumida T, Ishii R, Yokoyama S. Acta Crystallogr D Biol Crystallogr 69 5-15 (2013)
- Antibacterial 5'-O-(N-dipeptidyl)-sulfamoyladenosines. Van de Vijver P, Vondenhoff GH, Denivelle S, Rozenski J, Verhaegen J, Van Aerschot A, Herdewijn P. Bioorg Med Chem 17 260-269 (2009)
- Determinants for tRNA-dependent pretransfer editing in the synthetic site of isoleucyl-tRNA synthetase. Dulic M, Perona JJ, Gruic-Sovulj I. Biochemistry 53 6189-6198 (2014)
- Modeling of tRNA-assisted mechanism of Arg activation based on a structure of Arg-tRNA synthetase, tRNA, and an ATP analog (ANP). Konno M, Sumida T, Uchikawa E, Mori Y, Yanagisawa T, Sekine S, Yokoyama S. FEBS J 276 4763-4779 (2009)
- Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases. Kim SE, Kim SY, Kim S, Kang T, Lee J. Bioorg Med Chem Lett 15 3389-3393 (2005)
- Pharmacophore-based virtual screening: the discovery of novel methionyl-tRNA synthetase inhibitors. Kim SY, Lee YS, Kang T, Kim S, Lee J. Bioorg Med Chem Lett 16 4898-4907 (2006)
- A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions. Al-Moubarak E, Simons C. J Mol Model 17 1679-1693 (2011)
- Monitoring the Disassembly of Virus-like Particles by 19F-NMR. Leung RLC, Robinson MDM, Ajabali AAA, Karunanithy G, Lyons B, Raj R, Raoufmoghaddam S, Mohammed S, Claridge TDW, Baldwin AJ, Davis BG. J Am Chem Soc 139 5277-5280 (2017)
- Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. Schmitt E, Tanrikulu IC, Yoo TH, Panvert M, Tirrell DA, Mechulam Y. J Mol Biol 394 843-851 (2009)
- Identification and Characterization of a Chemical Compound that Inhibits Methionyl-tRNA Synthetase from Pseudomonas aeruginosa. Robles S, Hu Y, Resto T, Dean F, Bullard JM. Curr Drug Discov Technol 14 156-168 (2017)
- Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase. Ingvarsson H, Unge T. FEBS J 277 3947-3962 (2010)
- Mutations in MetG (methionyl-tRNA synthetase) and TrmD [tRNA (guanine-N1)-methyltransferase] conferring meropenem tolerance in Burkholderia thailandensis. Yi H, Lee H, Cho KH, Kim HS. J Antimicrob Chemother 73 332-338 (2018)
- Toward the catalytic mechanism of a cysteine ligase (MshC) from Mycobacterium smegmatis: an enzyme involved in the biosynthetic pathway of mycothiol. Fan F, Blanchard JS. Biochemistry 48 7150-7159 (2009)
- Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium. Mercaldi GF, Andrade MO, Zanella JL, Cordeiro AT, Benedetti CE. J Biol Chem 296 100658 (2021)
- Novel hybrid virtual screening protocol based on molecular docking and structure-based pharmacophore for discovery of methionyl-tRNA synthetase inhibitors as antibacterial agents. Liu C, He G, Jiang Q, Han B, Peng C. Int J Mol Sci 14 14225-14239 (2013)
- Toward an era of utilizing methionine overproducing hosts for recombinant protein production in Escherichia coli. Veeravalli K, Laird MW. Bioengineered 6 132-135 (2015)
- Identification and Characterization of Chemical Compounds that Inhibit Leucyl-tRNA Synthetase from Pseudomonas aeruginosa. Zamacona R, Chavero PN, Medellin E, Hu Y, Hughes CA, Quach N, Keniry M, Bullard JM. Curr Drug Discov Technol 17 119-130 (2020)
- Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Pang L, Zanki V, Strelkov SV, Van Aerschot A, Gruic-Sovulj I, Weeks SD. Commun Biol 5 883 (2022)
- Redesigning methionyl-tRNA synthetase for β-methionine activity with adaptive landscape flattening and experiments. Opuu V, Nigro G, Lazennec-Schurdevin C, Mechulam Y, Schmitt E, Simonson T. Protein Sci 32 e4738 (2023)
- MARS2 drives metabolic switch of non-small-cell lung cancer cells via interaction with MCU. Son J, Jung O, Kim JH, Park KS, Kweon HS, Nguyen NT, Lee YJ, Cha H, Lee Y, Tran Q, Seo Y, Park J, Choi J, Cheong H, Lee SY. Redox Biol 60 102628 (2023)