› 1pd0

X-ray diffraction
2.6Å resolution

Crystal structure of the COPII coat subunit, Sec24, complexed with a peptide from the SNARE protein Sed5 (yeast syntaxin-5)

Released:
DOI: 10.2210/pdb1pd0/pdb
PDB entry 1pd0 coloured by chain, front view.
PDB entry 1pd0 coloured by chain, side view.
PDB entry 1pd0 coloured by chain, top view.
Source organisms:
Primary publication:
SNARE selectivity of the COPII coat.
Mossessova E, Bickford LC, Goldberg J
Cell 114 483-95 (2003)
PMID: 12941276

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154123 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein transport protein SEC24 Chain: A
Molecule details ›
Chain: A
Length: 810 amino acids
Theoretical weight: 90.84 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P40482 (Residues: 117-926; Coverage: 88%)
Gene names: ANU1, SEC24, YIL109C
Sequence domains:
Structure domains:
Integral membrane protein SED5 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.19 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Not provided
UniProt:
  • Canonical: Q01590 (Residues: 201-210; Coverage: 3%)
Gene names: SED5, YLR026C

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P3221
Unit cell:
a: 94.527Å b: 94.527Å c: 197.935Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.206 0.254
Expression system: Not provided

Quick links

Citations

71 review citations

SNAREs--engines for membrane fusion.
Jahn et al. (2006)
70 more

2 mentions without citation

Sec24 phosphorylation regulates autophagosome abundance during nutrient deprivation.
Davis et al. (2016)
1 more