X-ray diffraction
2Å resolution

Structure of fully ligated Adenylosuccinate synthetase from Plasmodium falciparum


Function and Biology Details

Reaction catalysed:
GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Adenylosuccinate synthetase Chain: A
Molecule details ›
Chain: A
Length: 442 amino acids
Theoretical weight: 50.09 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9U8D3 (Residues: 3-442; Coverage: 100%)
Gene name: Adss
Sequence domains: Adenylosuccinate synthetase
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 91.579Å b: 117.117Å c: 80.416Å
α: 90° β: 90° γ: 90°
R R work R free
0.199 0.199 0.241
Expression system: Escherichia coli BL21(DE3)