1p6f

X-ray diffraction
2.2Å resolution

Structure of the human natural cytotoxicity receptor NKp46

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Natural cytotoxicity triggering receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 27.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O76036 (Residues: 22-263; Coverage: 86%)
Gene names: LY94, NCR1
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P61
Unit cell:
a: 85.731Å b: 85.731Å c: 59.52Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.207 0.251
Expression system: Escherichia coli BL21(DE3)