1oqd

X-ray diffraction
2.6Å resolution

Crystal structure of sTALL-1 and BCMA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 108-mer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor ligand superfamily member 13b, soluble form Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 144 amino acids
Theoretical weight: 16.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y275 (Residues: 142-285; Coverage: 51%)
Gene names: BAFF, BLYS, TALL1, TNFSF13B, TNFSF20, UNQ401/PRO738, ZTNF4
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Tumor necrosis factor receptor superfamily member 17 Chains: K, L, M, N, O, P, Q, R
Molecule details ›
Chains: K, L, M, N, O, P, Q, R
Length: 39 amino acids
Theoretical weight: 4.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02223 (Residues: 8-46; Coverage: 21%)
Gene names: BCM, BCMA, TNFRSF17
Sequence domains: BCMA, TALL-1 binding

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6322
Unit cell:
a: 232.854Å b: 232.854Å c: 212.477Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.24 0.26
Expression system: Escherichia coli