› 1oo7

Solution NMR

DNA.RNA HYBRID DUPLEX CONTAINING A 5-PROPYNE DNA STRAND AND PURINE-RICH RNA STRAND, NMR, 4 STRUCTURES

Released:
DOI: 10.2210/pdb1oo7/pdb
PDB entry 1oo7 coloured by chain, ensemble of 4 models, front view.
PDB entry 1oo7 coloured by chain, ensemble of 4 models, side view.
PDB entry 1oo7 coloured by chain, ensemble of 4 models, top view.
Source organism: Synthetic construct
Primary publication:
The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications.
Gyi JI, Gao D, Conn GL, Trent JO, Brown T, Lane AN
Nucleic Acids Res 31 2683-93 (2003)
PMID: 12736318

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-114317 (preferred)
Entry contents:
1 distinct DNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
5'-D(*GP*(5PC)P*(PDU)P*(PDU)P*(5PC)P*(PDU)P*(5PC)P*(PDU)P*(PDU)P*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.2 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.29 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 5PC 3 x 5PC

Experiments and Validation Details

Entry percentile scores
Refinement method: MULTIPLE STARTING CONFORMATIONS
Expression system: Not provided

Quick links

Citations

4 review citations

Click chemistry with DNA.
El-Sagheer et al. (2010)
3 more

1 mention without citation

Synthesis and properties of DNA oligomers containing stereopure phosphorothioate linkages and C-5 modified deoxyuridine derivatives.
Hara et al. (2020)