› 1oj6

X-ray diffraction
1.95Å resolution

Human brain neuroglobin three-dimensional structure

Released:
DOI: 10.2210/pdb1oj6/pdb
PDB entry 1oj6 coloured by chain, front view.
PDB entry 1oj6 coloured by chain, side view.
PDB entry 1oj6 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity.
Pesce A, Dewilde S, Nardini M, Moens L, Ascenzi P, Hankeln T, Burmester T, Bolognesi M
Structure 11 1087-95 (2003)
PMID: 12962627

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192480 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuroglobin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 151 amino acids
Theoretical weight: 16.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NPG2 (Residues: 1-151; Coverage: 100%)
Gene name: NGB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 4 x HEM
Ligand SO4 7 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 39.598Å b: 94.927Å c: 67.563Å
α: 90° β: 94.38° γ: 90°
R-values:
R R work R free
0.178 0.178 0.233
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

29 review citations

Neuroglobin: a respiratory protein of the nervous system.
Burmester et al. (2004)
28 more

24 mentions without citation

Neuroglobin, a Factor Playing for Nerve Cell Survival.
Guidolin et al. (2016)
23 more