1ohc

X-ray diffraction
2.5Å resolution

Structure of the proline directed phosphatase cdc14

Released:

Function and Biology Details

Reactions catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dual specificity protein phosphatase CDC14B Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 40.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O60729 (Residues: 39-386; Coverage: 70%)
Gene name: CDC14B
Sequence domains:
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF
Spacegroup: C2
Unit cell:
a: 114.702Å b: 51.937Å c: 65.07Å
α: 90° β: 118.34° γ: 90°
R-values:
R R work R free
0.201 0.201 0.277
Expression system: Spodoptera frugiperda