X-ray diffraction
2.45Å resolution

Multimodular Pneumococcal Cell Wall Endolysin from phage Cp-1 complexed with choline


Function and Biology Details

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Lysozyme Chain: A
Molecule details ›
Chain: A
Length: 339 amino acids
Theoretical weight: 39.28 KDa
Source organism: Streptococcus phage Cp-1
Expression system: Escherichia coli
  • Canonical: P15057 (Residues: 1-339; Coverage: 100%)
Gene names: 22, CPL1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 78.03Å b: 95.95Å c: 129.3Å
α: 90° β: 90° γ: 90°
R R work R free
0.205 0.205 0.264
Expression system: Escherichia coli