1oar

X-ray diffraction
2.23Å resolution

Fv IgE SPE-7 in complex with Alizarin Red

Released:
Source organism: Mus musculus
Primary publication:
Antibody multispecificity mediated by conformational diversity.
Science 299 1362-7 (2003)
PMID: 12610298

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IMMUNOGLOBULIN E Chains: H, I, J, K
Molecule details ›
Chains: H, I, J, K
Length: 122 amino acids
Theoretical weight: 13.69 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Structure domains: Immunoglobulins
Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104 Chains: L, M, N, O
Molecule details ›
Chains: L, M, N, O
Length: 110 amino acids
Theoretical weight: 11.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01724 (Residues: 20-128; Coverage: 99%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 78.917Å b: 78.882Å c: 169.036Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.205 0.241
Expression system: Escherichia coli