1o7v

X-ray diffraction
1.9Å resolution

High resolution structure of Siglec-7

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Sialic acid-binding Ig-like lectin 7 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.66 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q9Y286 (Residues: 18-144; Coverage: 28%)
Gene names: AIRM1, SIGLEC7
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P43212
Unit cell:
a: 40.049Å b: 40.049Å c: 140.769Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.258
Expression system: Cricetulus griseus