› 1o75

X-ray diffraction
1.95Å resolution

Tp47, the 47-Kilodalton Lipoprotein of Treponema pallidum

Released:
DOI: 10.2210/pdb1o75/pdb
PDB entry 1o75 coloured by chain, front view.
PDB entry 1o75 coloured by chain, side view.
PDB entry 1o75 coloured by chain, top view.
Source organism: Treponema pallidum
Primary publication:
Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein.
Deka RK, Machius M, Norgard MV, Tomchick DR
J Biol Chem 277 41857-64 (2002)
PMID: 12196546

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151566 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Putative DD-carboxypeptidase TP_0574 Chains: A, B
Molecule details ›
Chains: A, B
Length: 415 amino acids
Theoretical weight: 45.66 KDa
Source organism: Treponema pallidum
Expression system: Escherichia coli DH5[alpha]
UniProt:
  • Canonical: P29723 (Residues: 20-434; Coverage: 100%)
Gene name: TP_0574
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: PDX
Carbohydrate polymer
1 bound ligand:
Ligand XE 5 x XE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3221
Unit cell:
a: 128.931Å b: 128.931Å c: 151.161Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.205 0.205 0.228
Expression system: Escherichia coli DH5[alpha]

Quick links

Citations

6 review citations

Global challenge of antibiotic-resistant Treponema pallidum.
Stamm LV. (2010)
5 more