› 1nso

Solution NMR

Folded monomer of protease from Mason-Pfizer monkey virus

Released:
DOI: 10.2210/pdb1nso/pdb
PDB entry 1nso coloured by chain, ensemble of 10 models, front view.
PDB entry 1nso coloured by chain, ensemble of 10 models, side view.
PDB entry 1nso coloured by chain, ensemble of 10 models, top view.
Source organism: Simian retrovirus 1
Primary publication:
Three-dimensional structure of a monomeric form of a retroviral protease.
Veverka V, Bauerová H, Zábranský A, Lang J, Ruml T, Pichová I, Hrabal R
J Mol Biol 333 771-80 (2003)
PMID: 14568536

Function and Biology Details

Reaction catalysed: 
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139633 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protease 13 kDa Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.19 KDa
Source organism: Simian retrovirus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P07570 (Residues: 760-866; Coverage: 12%)
Gene name: gag-pro
Sequence domains: Retroviral aspartyl protease
Structure domains: Acid Proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Precursors of Viral Proteases as Distinct Drug Targets.
Majerová et al. (2021)
9 other articles

6 mentions without citation

A consensus view of protein dynamics.
Rueda et al. (2007)
5 more